My 11 year old son Kevin is high functioning and has been on risperdal for nearly 8 years and had been doing very well. However, his neurologist feels he is beginning to outlive it's effectiveness and safety limits. She is recommending SSRI's, specifically Luvox. I've read all the possible side affects and warnings and stigmas and they are enough to make my head swim. Just wondering if anyone else has had any experience with luvox and how well it worked, or didn't work. Any input would be greatly appreciated.
God Bless....In HIS Service....Dan

Hi Dan

my son was given Luvox to help with OCD

it had horrid side effects in him and helped very little.

do be very careful with this one.

You may also want to ask about itn on the Medications forums here
http://neurotalk.psychcentral.com/forumdisplay.php?f=72

Sorry to be late to this thread---but alot of research was needed to bring facts here.

When a parent company withdraws a drug voluntarily from the US market, beware.

This is done to avoid liability. Luvox is no longer available in US from Solvay.
The drug is available as fluoxamine generic. Should you need to sue for damages, Solvay is not liable any longer.
Solvay sold their patent to another company JAZZ. (Somehow this name is rather disturbing for a drug company! (It is a subsidiary of Solvay however).

from http://www.emaxhealth.com/94/14611.html

and this link:
http://www.reuters.com/article/compa...EN009220070802

http://www.fda.gov/bbs/topics/ANSWER.../ANS01283.html
(2004)

At the time Luvox was approved here, there was a situation with one of the trial doctors who falsified information.

Medwatch data:
http://www.fda.gov/medwatch/safety/2000/jun00.htm#luvox
serious issues.

Here is a link to reported serious events with fluvoxamine in 2007:
http://patientsville.com/medication/...de_effects.htm
Keep in mind it is not commonly used, so the reports are few.
But the ones there are pretty serious.

Luvox was in the news heavily about the Columbine shootings. There is information on the net suggesting one of the young men was using this drug in high doses. A lawsuit resulted. Mania and psychosis are in the drug information side list for Luvox.

Since fluvoxamine has more specificity for serotonin receptors, the side effects of suicide and aggression may be higher, IMO for it.

This drug certainly has a checkered past. I would be hesitant to put my child on it for any reason.

As an aside: L-tryptophan is now available without prescription in US (since this summer). You can discuss with
your doctor trying this to raise serotonin more gently--and it works best with B6 added too.