Hi MelodyL

A couple of thoughts:

I stumbled upon the info that it can be caused by a mutation of the Card 14 gene in a person's body.

Abnormal forms of the protein coded for by the CARD14 gene have been linked to psoriasis. These proteins are expressed on various kinds of skin cells. There is a very technical but free-access account of this work here: http://www.ncbi.nlm.nih.gov/pubmed/22521418 .

I wonder if stem cell therapy would work on people with psoriasis.

My understanding of current biomedical knowledge suggests that stem cell therapy would not be effective for people with psoriasis. It can be effective for people with some blood cell cancers (it is called a bone marrow transplant in this context).

What is done for these patients is to treat them with a very high dose of a chemotherapeutic, which will kill all of the stem cells in the bone marrow which make blood cells (including those which make the cancerous blood cells).

A bone marrow transplant from a healthy donor will supply healthy stem cells which will make healthy blood cells.

As far as I know there is not yet any way of doing the equivalent for people with CARD14 mutations - there is no current way of selectively killing the various kinds of skin cells which make the abnormal form of CARD14 and replacing them with healthy skin cells.

Apologies if this is a bit technical.

Hi Melody,

I also have psoriatic arthritis and skin psoriasis.
My skin psoriasis is very limited, so far, to my elbow and a couple of nails.
I am very lucky, I know.

Many people with moderate to severe skin psoriasis (Ps) are reporting amazing results with a 1:1 mixture of (liquid) glycerin and alcohol-free witch hazel. They mix this solution, place it in a spray bottle and spray it on 3-4 times a day. This is the most popular CAM approach right now. Many excellent testimonials to this approach.

Others are doing a similar mixture with raw apple cider vinegar and glycerin at the same 1:1 mix.

Some are very happy with the skin healing they are getting from applying coconut oil directly to the Ps lesions.

Many swear by a paleo diet.

Many meds used for psoriatic arthritis (PsA) tend to aggravate the skin Ps.
These can include NSAIDs, Plaquenil and others.

I have not been around NeuroTalk for awhile, so I don't know what Alan has tried. The remedies I have mentioned above are some of the newest and "greatest" natural approaches within a large international group of people living with Ps and PsA.

There is a new med people like. it is not a "biologic" type, it is called Otezla.
Many swear it clears up their skin well.

I hope I have mentioned something helpful.

To Our Healing,
DejaVu

Hi there.

Alan has used it all. Had the laser thing done twice. Worked the first time. Did nothing the second time. We have tried every cream on the market and some that are NOT on the market.

Nothing works. If he is stressed it comes out even more. Since he has neuropathy pain all the time, that is his stressor.

Nothing to be done. Some times its a bit better, sometimes I find scales all over the place.


Ah well. Thanks much for replying and trying to help.

Mel

Mel, I have heard anecdotally of good results for psoriasis with application of topical Hemp Seed Oil.

You wrote:

"As far as I know there is not yet any way of doing the equivalent for people with CARD14 mutations - there is no current way of selectively killing the various kinds of skin cells which make the abnormal form of CARD14 and replacing them with healthy skin cells.

Apologies if this is a bit technical."

You can get as technical as you like. Because I correspond with Glenn, he explains everything to me and I can now understand much of what is technical. I just did a search of the CARD 14 mutations. OMG, poor Alan. He doesn't stand a chance does he?

Both genetics (his family members have it also) and whatever triggered it.

We'll never know.

I just took a look and holy moly, they are now all red. I put some of that healing cream on it.

I don't see this going away any time soon. All we can do is continue the anti-candida diet and maybe, just maybe it will calm down a bit.

The more I learn, the more I know.

Thankfully I like to learn stuff.

But have you ever seen the guy on youtube. Just type in "Worse case of psoriasis". His videos are all over the place. Please, explain what the heck happened with this guy, he has this all over his body. He just uses a knife, or duct tape, or wax, or whatever (he experiments) and people just tune into him scraping the scales off of his skin. I mean, I NEVER saw such a case of psoriasis. He MUST have this mutation right?

Thanks much
Melody

I got scalp psoriasis on my face from few months, any treatment for this?

Hi Vikrambatra884,

Welcome to NeuroTalk!
Please make yourself at home here.

As for your question, I'm assuming you have been diagnosed with scalp psoriasis? This then spread to your face?

There are many approaches one may use to try to heal the psoriasis.

You may call your doctor and obtain a prescription cream.

You may try an alternative method, like those mentioned above.

I hope this helps.

Again, welcome to NeuroTalk!

DejaVu

I have been dealing with some scaling on my face; especially forehead and hairline/scalp. The dermatologist I saw diagnosed this as Seborrheic/Seborrhea Dermatitis.

I also have been dealing with some eruptions on my shoulders which the doctor said were second cousin to Psoriasis. My elbows have some scaling as well. The doctor said this was Psoriasis. My dermatologist says; "all of these issues are either Psoriasis or 2nd cousin to Psoriasis.

I was prescribed Promiseb which is a topical cream for my face (use daily) and can be used for shoulders, as well as elbows.
The doctor also told me to use Selsun Blue Dandruff Shampoo once or twice a week to control the scaling for the hairline/head. This has improved these issues; but is something that will likely be ongoing.

Dermarest Psoriasis Mediated Treatment Gel has helped limit the shoulder and elbow issues, as well as the Dermarest Psoriasis Medicated Moisturizer (both of these can be purchased at Walmart). I use these two every evening before bedtime. These have improved my issues; but will need to be used daily as well.

Not sure if this info will be helpful; but thought it might be worth looking into.



Gerry

Hi ger715 and vikrambatra,

I don't know what I was thinking when I had last posted. I think I was tired and had forgotten to mention these products/approaches.

Earlier in the thread, I had mentioned some "natural" remedies being reported as very helpful to many with skin psoriasis. Large groups of people are finding the natural topicals (noted earlier in the thread) as very helpful.

My scalp is always threatening to flare. I've been able to keep that under control by rotating a shampoo formulation named MG217 and Nizoral shampoo, along with a very gentle shampoo. This rotation of these shampoos helps me more than the VERY expensive prescribed shampoos.

(Both are OTC. I had read an article quite some time ago , written by a dermatologist, suggesting these two type of products be rotated to keep the scalp in check. MG217 is a lightly scented coal tar shampoo. Nizoral shampoo contains Nizoral, which is an anti-yeast medication.)

MG217 products in general -- shampoos, creams and gels -- are recognized by the National Psoriasis Foundation and this in on the bottles of MG217 bottles. If one is looking for an OTC product, the MG217 products are suggested at the NPF site.

Another OTC product, most healing for my elbow psoriasis is: Psoriasin Gel.
This is also an OTC recommendation made on the official NPF site.
The dermatologist has suggested rotating the OTC Psoriasin Gel with a topical (prescribed) triamcinolone acetonide USP 0.1% ointment (a weak steroidal ointment).

These are relatively low-cost approaches, compared to most prescribed new formulations for psoriasis.

A prescribed scalp treatment I use on rare occasions, when things are flaring more: betamethasone valerate lotion USP, 0.1% (on scalp). This puts the fire out, right away.

This approach would not be adequate for someone covered with skin psoriasis.
This approach is an approach for people with mild scalp issues and/or small areas of psoriasis-- like elbows, etc.


Geri, the Dermarest formulations sound very interesting! Thanks for mentioning those, along with mention of the prescribed cream you use.
I will check them out.


As for prescribed topicals and shampoos, there are so many available, it gets confusing. In my case, the OTC approaches are working well enough at this time.

Many people will suggest tea tree oil shampoo. This is usually okay to use once a week, as it's usually very drying to the hair and scalp and using it more often may aggravate the scalp.

I have found various medications often set off a scalp flare. My scalp will feel like it's on fire and it all goes quickly downhill from there. I have to stop the offending medication immediately.

To Our Comfort and Healing,
DejaVu