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Old 05-29-2010, 08:34 AM #1
dogodlvr dogodlvr is offline
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Confused herbal treatments

My psycologist like to try herbal remidies.. he is in the same group as the psyciatrist I see who works with my perscribed meds.
Has anyone tried D-L Phenylalanine? It stimulates dopimine in the brain. I react to all antidepressants. How about HGH.
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Old 05-29-2010, 08:55 AM #2
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Default hi Pam

hi Pam. i'm sorry you can't take antidepressants.

i would DEFINITELY consult with your pdoc as well, before taking any 'supplements' on tdoc's (or anyone's) suggestion. some supplements interact with meds or can be contraindicated for certain conditions. your pdoc is a medical doctor who can fully evaluate the pharmacological implications with respect to your medical situation. tdoc is not qualified to do this.

HGH (Human Growth Hormone) sounded suspicious to me on principle - i found an article you might find intersesting:

http://www.quackwatch.org/01Quackery...opics/hgh.html

phenylalanine is contraindicated if you have phenylketonuria, but your doc would know that. note that phenylalanine level increase is associated with regular use of aspartame. it is also associated with seizure risk - again, a concern if you have seizures - many medications increase risk of seizures but for most people they do not present a problem. i have migraines so i personally would not want to try phenylalanine. (there is conflicting information, but some sources suggest it can trigger migraines.)

there are always risks as with many prescribed meds. if you are not in a specific risk group, i.e. have phenylketonuria, epilepsy, migraines, and pdoc agrees it is ok to take the supplements, i would simply suggest caution and moderation - as with anything really.

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Old 05-29-2010, 12:12 PM #3
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Phenylketonuria and Aspartame

This sugar substitute, sold commercially as Equal and NutraSweet, was hailed as the savior for dieters who for decades had put up with saccharine's unpleasant after taste. There are quite a few problems with aspartame. The first is phenylketonuria (PKU). One out of 20,000 babies is born without the ability to metabolize phenylalanine, one of the two amino acids in aspartame. Toxic levels of this substance in the blood can result in mental retardation. Beyond PKU, several scientists believe that aspartame might cause altered brain function and behavior changes in consumers. And many people have reported the following side effects from aspartame:
  • Fibromyalgia Syndrome and symptoms of Fibromyalgia
  • Multiple Sclerosis symptoms
  • Dizziness
  • Headaches
  • Menstrual problems
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Old 05-29-2010, 01:53 PM #4
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Default Check with psychiatrist. Also with pharmacist.

Hi,

It's good to check with the pdoc, but the pdoc might now know enough about it to discuss it. At least let the pdoc know.

I found abstracts of articles about this.
It has been studied.


>> http://www.springerlink.com/content/q6r166283135401h/
Quote:
It is concluded thatdl-phenylalanine might have substantial antidepressant properties. However, certain methodological considerations still warrant a careful interpretation.
=-=-=

>> http://ajp.psychiatryonline.org/cgi/...ct/137/12/1611
Quote:
Only two of the eleven patients had any therapeutic effect from the drug . . .
This article mentions slight heartburn.
=-=-=

>> http://www.ncbi.nlm.nih.gov/pubmed/1173765
Quote:
To 23 subjects with endogenous depression after a previous unsuccessful treatment with common antidepressive drugs (imipramine-like or MAO inhibitors) dl- or d-phenylalanine was given in dialy oral doses of 50 or 100 mg during 15 days. A complete euthymia was obtained in 17 subjects between one and 13 days of treatment. No important adverse reaction was observed.
=-=-=

I'll look for more later.
It is nice that your psychologist is looking out for you.

M.
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Old 05-29-2010, 02:21 PM #5
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Lightbulb

d-phenylalanine can raise blood pressure, so this should be monitored.

I'd suggest l-typtophan instead.

Also if you feel depressed, I'd get your Vitamin D tested.
Low D is connected to depression. I haven't needed my SAD light visor since upping mine to 5000IU daily this winter. (I don't take it on days I am outside alot).

Also useful for depression is methylfolate (folic acid). There is even an RX version called Deplin:
http://www.deplin.com/HealthcareProfessionals,Trials

Folate may be too energizing however, for some people.

Another thing that works well for depression is DHA (part of the oil in fish oil). There are vegetarian versions of DHA too.
One is called Expecta, and can be found in most vitamin sections in larger stores.

SAMe is the most commonly used supplement for mood improvement. However, it may be too energizing for bipolar patients, so if you try it, start low at 200mg a day and increase very slowly.

I'd try the tried and true proven interventions before considering the weird ones like HGH or d-phenylalanine!
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Old 05-29-2010, 04:25 PM #6
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Dear Pam,

My vit D was very low when my mdoc checked. So was my hubby's.
When mdocs test for it, they find it.

Get the vit D checked. Also B12.


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Old 07-07-2010, 08:10 PM #7
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Smirk hanks all.. It's good to know you are here

Thanks all. I have been taking high doses of perscription Vit D for the last 18 months. I get my blood work repeated next month. I also take 5000 mg
B-12. So I hope I am good there. I tried Sam-E once.. right into hypomania..
All antidepresants send me manic.
I have in the last month added 1 mg of abilify, small doses increase seritonin, I also did add the DL-phenylalanine. (to produce more dopamine) It actually seems to be working. I went 4 1/2 weeks feeling pretty good. Scale 1- 10 I stayed a 7-9 each day and just a little wired. My drop to a 4 only lasted a day.. I stay in a mixed state/ rapid cycle most of the time so this little bit of relief is welcomed.
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Old 07-08-2010, 03:49 AM #8
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Thumbs up

Hi,
Thanks for the update. It's good to hear from you.
THat's good about the DL-phenylalanine helping.

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Old 07-08-2010, 07:15 AM #9
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Lightbulb

Prescription D2 is not very effective. It is an antiquated treatment.

I'd suggest you switch to D3. It is over the counter and the active form of D. I suspect your levels will not be ideal with the D2.

Your target is 50-80ng/ml.
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Old 07-09-2010, 08:18 PM #10
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Hello there Pam it's nice to hear from you, and that your treatments are helping.

do check what type of vitamin D you are taking... i can't remember where you are... where i live the prescription kind is in fact D3 (cholecalciferol) but in the US i do believe D2 (ergocalciferol) is the usual prescribed form.

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