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-   -   Slight problem, unsure of necessary approach (https://www.neurotalk.org/bipolar-disorder/194529-slight-unsure-approach.html)

bizi 09-25-2013 07:34 AM

wonder if you could take plain benadryl? for some people it makes them tired, use it as a sleep aid, others it does the opposite.
Did you call your md?
bizi

mrsD 09-25-2013 07:40 AM

Quote:

Originally Posted by _belle (Post 1017311)
I take Fluoxetine, Tramadol (PN)and on/off Codeine Phosphate (I think!). I have antihistamines, but it's one that says it doesn't make you drowsy.

I've been meditating a lot anyway, (I'm buddhist!) and I've had a bit more support having spoken up about my issues. It's still hard, but there's only a day left until my meds are back. Thanks a lot for all the suggestions!

Hi there... I have searched a drug checker for you.
Here are the results:
http://www.drugs.com/interactions-ch...221-0,1115-648

There is a major interaction between tramadol and SSRI drugs like Prozac. Your doctors should be made aware of this, as sometimes they don't know all the interactions out there.

waves 09-25-2013 08:14 AM

Hi again, and further notes on interactions
 
Hi Belle,

I am glad you are getting your meds back! :)

The interaction MrsD was talking about -- it's basically that both Tramadol and Fluoxetine increase serotonin levels because both inhibit serotonin reuptake (SSRI action). The danger is Serotonin Syndrome, which can be fatal, so do, please, discuss your treatment plan with your doctor.

I'd like to add something though. Even if you do not develop this syndrome you can end up with excessive serotonin in the nervous system. This can cause symptoms like undue nervousness, agitation, muscle tension, and possibly excessive sweating. You could also have emotional symptoms like dysphoria, manic reaction, or if your mood was already off, the combination of these drugs could make it worse. It isn't all or nothing: one can get any subset of these symptoms to any degree.

---------------
If you ever take triptan drugs (for migraine) or cough medicine/drops containing dextromethorphan, these meds will further contribute to the interaction (increased risk of Serotonin Syndrome), so ask your physician about these as well, if applicable.

---------------
I've used sertraline (an SSRI like fluoxetine), tramadol, and zolmitriptan concurrently but only the sertraline was a daily drug. All three of my doctors were aware of all the meds, but only my neurologist seemed conspicuously aware of the interactions. He advised to make a dosage adjustment to the sertraline when I had to use one of the other two.

waves


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