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Old 06-04-2012, 12:14 PM #11
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Default Re: Opioid Conversion Calculator...
Here is a newer (as of this post) Opioid Conversion Calculator (same disclaimers apply) developed by three pain experts, based on latest up-to-datest medical evidence, for Practical Pain Management (PPM).

The first link is the introductory article that discusses conversions (tables, calculators) in general and this new one specifically, including background information, safety concerns, and special cases like methadone. I encourage everyone to read it before jumping to the calculator (There WILL be a QUIZ! )

PPM Launches Online Opioid Calculator

Thereafter, the direct link is:

Opioid Calculator

Doc
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Oh, the pain... THE PAIN...

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Old 06-04-2012, 03:02 PM #12
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Default Hormones and Chronic/Intractable Pain
Quote:
The effect of severe, persistent pain on the hormone system is profoundly negative. If the patient’s hormone system is not kept homeostatic and balanced, the patient with pain will rapidly age and deteriorate. Episodic excess of cortisol in the blood, which occurs during pain flares, is particularly deleterious. Consequently, the achievement of hormonal balance—not too high or too low—has to be a primary goal of treatment.

Unfortunately, some of the potent pain medications, particularly opioids, may suppress the production of some adrenal and gonadal hormones, especially testosterone and pregnenolone, and need to be replaced. If any major adrenal or gonadal hormone becomes deficient during ongoing opioid treatment, the patient likely will not respond well to the prescribed pain medication and may report and exhibit such symptoms as poor pain control, depression, mental impairment, insomnia, allodynia, and hyperalgesia.
—Forest Tennant, MD, DPH
http://www.practicalpainmanagement.c...ance-pain-care
Brain Atrophy with Chronic Pain

The Intractable Pain Patient's Handbook For Survival by Forest Tennant, MD, DPH

Hormone Therapy for Chronic Pain

Hormone Replacement Therapy in Morphine-induced Hypogonadic Male Chronic Pain Patients
Quote:
CONCLUSIONS:
In conclusion, our results suggest that a constant, long-term supply of testosterone can induce a general improvement of the male chronic pain patient's quality of life, an important clinical aspect of pain management.
Testosterone Replacement in Chronic Pain Patients

Testosterone Replacement in Female Chronic Pain Patients

From Research To Practical Application: Long Term Testosterone Treatment

Hormone Treatments in Chronic and Intractable Pain An Emerging Practice

Hormone Replacements and Treatments in Chronic Pain: Update 2010

Hormone Therapies: Newest Advance in Pain Care

Human Chorionic Gonadotropin in Pain Treatment

HCG and Diabetic Neuropathy

HCG and Testosterone

Cortisol Screening in Chronic Pain Patients

I'm seeing some references to the hormone oxytocin (not to be confused with the opioid pain medication Oxycontin) having much potential, but as yet, I have not seen much else. It is very early in its investigation.

Oxytocin May Offer Benefits in Treatment of Chronic Pain

Intrathecal Administration of Oxytocin Induces Analgesia in Low Back Pain Involving the Endogenous Opiate Peptide System Study done on rats. As Good Ol' Charlie Brown would say, "RATS!"

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Dr. Zachary Smith
Oh, the pain... THE PAIN...

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All opinions expressed are my own. For medical advice/opinion, consult your doctor.
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"Thanks for this!" says:
spine95 (06-04-2012)
Old 07-01-2012, 04:44 AM #13
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Lightbulb The Hurt Blocker: Science News article:
This June 2012, Science News has a very interesting article on
specific sodium channels in the peripheral nervous system, that may be targets for non-opiate blocking drugs eventually. This may lead to the development of pain relieving drugs with few side effects.

http://www.sciencenews.org/view/feat...e/Hurt_Blocker
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Old 10-08-2013, 12:29 PM #14
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Default
Here's a series of well-written easy to understand articles on various chronic pain topics from eorthopod.com.

Adult Pain Management Patient Guides

Topics Include:
  • Body Talk (A complimentary/alternative medicine approach)
  • Chronic Pain and Nutrition
  • Chronic Pain and Sleep
  • Chronic Pain Management
  • Complex Regional Pain Syndrome (CRPS)
  • Epidural Steroid Injections
  • Facet Joint Injections
  • Injections for Pain
  • Medication Approach to Chronic Pain
  • Pain Management Medications
  • Pain Pumps
  • Piriformis Muscle Injections
  • Radiofrequency Ablation
  • Relaxation Training
  • Sacroiliac Joint Injections
  • Spinal Cord Stimulators (SCS)
  • Transcutaneous Electrical Stimulation (TENS)

Doc
__________________
Dr. Zachary Smith
Oh, the pain... THE PAIN...

Dr. Smith is NOT a medical doctor. He was a character from LOST IN SPACE.
All opinions expressed are my own. For medical advice/opinion, consult your doctor.
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