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Old 09-11-2008, 09:03 AM #1
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vini vini is offline
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vini vini is offline
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Join Date: Aug 2008
Location: some were over the rainbow
Posts: 552
15 yr Member
Default CSF health

hello all

any other CSF leakers taking ATENOLOL !!!!
I would like to start by saying Atenolol and all beta blockers undoubtedly save life's and no one should just stop taking them *doc, I will be consulting my doctors to see if there is an alternative medication, I can take for my high blood pressure that dose not affect the choroid plexus and CSF production, as most of us on this board know CSF high ,low volume /pressure all have painful and devastating affects on our lives , also our cognitive ability s, as we know our CSF supports, nourishes, cleanses by removing spent neurons and toxins from our brain and spinal cord in a cyclical motion . So from this article

ARTICLES
The nocturnal increase in human cerebrospinal fluid production is inhibited by a beta 1-receptor antagonist

C. Nilsson, F. Stahlberg, P. Gideon, C. Thomsen and O. Henriksen
Department of Medical Cell Research, University of Lund, Sweden.

A circadian variation in human cerebrospinal fluid (CSF) production has recently been demonstrated using magnetic resonance phase imaging. A nightly peak in CSF production was found at approximately 0200, when production is approximately twice the daytime values. In the present study, we have investigated the effect of a beta 1-receptor antagonist, atenolol, on the production of CSF, specifically the nocturnal production peak. CSF production was measured in fourteen healthy volunteers of both sexes in the time interval 1500-1800, with or without drug administration (100 mg orally) at 1800, and a second measurement was made in the time interval 2300-0200. In the absence of drug administration, all nine volunteers showed a significant increase in CSF production at night, from 0.34 +/- 0.06 ml/min in the time interval 1500-1800 to 0.61 +/- 0.05 (SE) ml/min (P < 0.005), confirming the presence of a circadian variation in these individuals. One week later, the experiment was repeated in five of these volunteers, plus an additional five volunteers, but with the administration of 100 mg atenolol orally immediately after the first measurement (at 1800). In five of the volunteers a decrease in CSF production was seen at midnight compared with daytime production values; in two volunteers CSF production remained unchanged, while three volunteers showed increased production. The average CSF production was 32% lower at night (0.27 +/- 0.10 ml/min) compared with the afternoon (0.40 +/- 0.07 ml/min), after administration of atenolol (P = 0.37).(ABSTRACT TRUNCATED AT 250 WORDS)


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the research suggests that atenolol lowers CSF production by 32% at night now my partner has told me I have fits in my sleep ( interesting ) for those who don,t know me . I suffered head trauma had a nasal CSF leak from skull fractures I think I am still leaking and starting tests soon , so for any one with with CSF leaks or in fact any one with a neurological condition ,are these type of drugs in conflict with our health ? undoubtedly beneficial to our cardiovascular system, but compromising our CSF production / balance of this delicate system? ( a true dichotomy ) I have been on atenolol 100mg for two years many of my problems maybe due to the TBI and the leak but anything thats is effecting my system cant be helping us to heal
so lets run with this thread and see were it takes us
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the light connects the many stars, and through the web they think as one, like god the universe we learn about our self's, the light and warmth connect us, the distance & darkness keep us apart
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vini
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Last edited by vini; 09-11-2008 at 09:53 AM.
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