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Switching AD?

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Old 05-02-2007, 07:40 PM #1
Viriatus Viriatus is offline
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Viriatus Viriatus is offline
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Arrow Switching AD?
Hi.

I am now taking clomipramine (anafranil), which is a tryciclic AD. I take 50 mgs/day. It worked for me in the past, but now I still feel depressed and anxious. I think I might have to go and try another AD, like lexapro, effexor or paroxetine. I just don't now if I can mix the two and slowly drop the anafranil, or if I have to drop anafranil first. Anyone have any thoughts?
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Old 05-03-2007, 03:40 PM #2
JD3#2 JD3#2 is offline
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The usual recommended procedure is to drop one or the other. In other words tricyclics and ssri's can interact to produce a serotonin overload which can be a very bad--even fatal happening.

However I don't know the specifics as to lowering one while rasing the other etc. This is something which should be handled by the professionals--dr, pharmacist, etc.

Take care
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