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Diabetes / Insulin Resistance / Metabolic Syndrome For discussion of Type 1 and Type 2 diabetes, insulin resistance and metabolic syndrome. |
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05-20-2013, 01:06 AM | #1 | |||
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I was diagnosed in October 2012, and placed on Metformin, Glyburide and Lisinopril.
Once I got past the thrills of starting Metformin, I developed a persistent dry cough, headaches and extreme fatigue....research has brought to my attention that these are common side effects of ACE inhibitors which is the drug class Lisinopril belongs to. I cough until I can't breathe, or gag and vomit. Night & Day!! Has anyone else experienced this? All of this - and my sugars are consistently between 88 & 124!
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Kimberly M. Fowler Each player must accept the cards life deals him or her: but once they are in hand, he or she alone must decide how to play the cards in order to win the game. -- Voltaire dx'ed w/Young Onset Parkinson's Disease May 2006 at age 43. Symptomatic since 1997 or earlier. DBS June 22, 2010 dx'ed w/TN on right side 2007. GK x4, last GK 02/2013 |
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05-20-2013, 01:39 AM | #2 | |||
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Wisest Elder Ever
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The reason for the cough is something to pay close attention to.
The agent is bradykinin, which builds up in some people because they are low in the enzyme that degrades it. The cough can be a serious warning sign of angioedema. It can swell your throat until you cannot breathe at all. I had this happen to me this winter...I swelled up all over and had terrible pain. So please contact your doctor and get that drug changed and never take it again! Acquired angioedema is a real, life threatening situation: http://www.hcplive.com/publications/...-04/2005-04_02 You may or MAY NOT have hives with this. Mine did not have hives at all. I took ACE inhibitors for about a decade, but the lisinopril was the last straw. Evidently, my metabolism could not handle it (previously on Vasotec) and I had a very painful crisis. You can die from this if your throat swells up enough. So you must report your severe cough now, and get off all ACE inhibitors. http://www.haea.org/about/ Doctors are now getting Continuing Education on this subject, as up til now it has been hidden and not recognized. People inherit the inability to remove bradykinin from the body, in various degrees, and the special blood tests on the HAEA website explains them, and how to interpret them. It is best to find a specialist called an immunologist for this evaluation. One thing doctors do not often understand about Lisinopril.. This drug is excreted whole (unmetabolized) in the urine...and for me at least this caused terrible bladder pain when I had my reaction. This can simulate a bladder infection, but it is not. If you have this bladder symptom, it is just another reason to get your doctor to give you another blood pressure treatment. NO MORE ACE inhibitors!
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06-03-2013, 07:40 PM | #3 | |||
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As far as I know, Lisinopril is for blood pressure, not for blood sugar. Are you hypertensive? ok quick google/wikipedia says it is used for prevention of renal and retinal problems in diabetics...
I was given lisinopril and did fine for a few months, but did develop a horrible cough about 3 months later, I wasn't sure if it was from the med or a reaction from a cold/virus that I'd been trying to recover from. The cough was worst when I was talking on the phone, which was very weird for me. Most of my post-cold coughs were bad at night, and this one was, but the phone-speak-cough was just awful. I eventually ditched all new meds, got some prednisone (doc prescribed) and went back to my metoprolol, no more cough. ACE inhibitors are known for causing a dry cough. I agree with MrsD, get it checked out and see about getting your med switched to something else. |
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