There has got to be someone out there who has experienced this or can shed some light on the problem. On March 1, 2007 I was diagnosed t-2 . The previous year I was pre-diabetic. I had no diabetic symptoms and the t-2 was diagnosed from my yearly physical. I started my oral med on March 15 and My glucose levels responded very well immediately. After a period of about 1 week I started experiencing Neuropathy symptoms! Burning pain in my feet, legs ,hands, arms , some so intense that I am now taking Lyrica for the pain. This neuropathy was literally overnight and It sure seems strange that it occurred so quickly and completely upon good control. Any clues?

hi flsun01. welcome to neurotalk.

here is the link to our PN forum. i know some there have diabetes. i;m sure they will be of great help.

http://neurotalk.psychcentral.com/forumdisplay.php?f=20

--neuropathy linked to diabetes/impaired glucose tolerance does not always occur slolwy and insidiously; it can happen quite abruptly, especially to those who are newly diagnosed and are suddenly attempting to get blood sugar levels under control, especially through medications.

Take a look at:

http://www.neuro.wustl.edu/neuromusc...etes.htm#acute

http://www.cfpc.ca/cfp/2001/May/_pdf...-may-cme-2.pdf

http://www.blackwell-synergy.com/lin...7.2003.03009.x

Well , thnx glenntaj , I figured there had to be some kind of explanation for my rapid decline. My GP says; " well it is neuropathy", hell I knew that before I got there! I just wanted an explanation as to why I felt like hell within a WEEK of starting my medicine. I had my first follow-up lab last week and my a1c is 6.6, the doc is raving about how great my numbers look and I am dying of pain! Looks like you can lower glucose too much and too fast. My nerves seemed to be a lot happier in their old enviroment of glucose and high lipids lol!

We have diabetics, and all other sorts there.. and I like to think we're all a bit nuts about and with the pain! - j

I had acute onset of PN symptoms, mine was caused by prediabetes & low b12.
I wouldn't have a clue how long i was in a prediabetic state, maybe years i was damaging my small fibres nerves before they were really damaged which of course brought on PN symptoms, with like eletrict zaps, intense burning, and numbness on the soles of my feet.
That was roughly 4 years ago, i went off all high sugary carbs, eat a sensible diet, some exercise in the local pool [ non weight bearing] lost a fair bit of weight and have successfully reversed the prediabetic state, i very seldom get any burning, probable once in a blue moon no more zapps or anything elseassociated with PN.
Prediabetes can be reversed and nerves can and do regenerate once there in the right enviroment, but they do take some time.
good luck
Brian

I don't know how often instant neuropathy may happen but you are not alone. If you look up the story of Mother Dolores Hart, who is a spokesperson for the Neuropathy Assoc. -- it show that her's came on all at one time after a root canal of all things.

Ron