New Member
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Join Date: Jan 2021
Posts: 3
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New Member
Join Date: Jan 2021
Posts: 3
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neuropathy caused by sodium-pump defect?
I posted this NIH article in the peripheral neuropathy forum where the OP asked if anyone noticed a correlation between salt intake and severity of their neuropathy symptoms. I recently noticed a similar relationship in my non-diabetic neuropathy.
I'm just now looking into sodium-related neuropathy and came across an article that talks about a sodium pump defect in diabetic neuropathy, so I thought I would also cross-post in this forum.
A sodium-pump defect in diabetic peripheral nerve corrected by sorbinil administration: relationship to myo-inositol metabolism and nerve conduction slowing
Nerve conduction slowing, a hallmark of both experimental and human diabetic neuropathy, is improved or corrected by aldose reductase inhibitors such as sorbinil.
Not enough posts for a direct link but it's a pubmed NIH document 2421135.
I'm wondering if anyone has already looked at this or has some experience with sorbinil or other aldose reductase inhibitors.
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