Savella was the most recent drug to be approved for FMS. It is another type combo Antidepressant. I had a very bad reaction to it that made me feel like I was flaring for one month. My Rheum said it was the drug so I just d/c it.

Also, my Rheumatologist mentioned that Tapentadol ER (extended release) manufactured by Ortho-McNeil will be available next month. He feels it will be a good drug for FMS. It is a Oxycodone-type narcotic mixed with a Norepinepheran reuptake.

Dosage is two pills a day which is probably cleaner than taking multiple dosages of Loratab and daily Welbutrin. Nothing really new and wonderful though...

Mere

Hmmmmm, sounds like it might be promising. If you go on it, let us know how it works....

I took Savella for the two week titration pack and felt the worst flair I have ever had...terrible!

I have also been on Tramadol...I feel it is a sugar pill. No relief for pain. I take a handful...not really but it feels like it...of Aleve and have gone back to my Lortab. I do take Wellbutrin and muscle relaxers. When I get the feels like my skin is crawling I take a Xanax and it does take most of it away. I just want to go back to my Lortab and forget about all the new or old Fibro drugs! Thanks for caring and for all of the suggestion. It is always good to know what works for everyone else…

Thanks Tammi for letting me know about that. I'm sorry you had a bad time with that, which means I probably would too as I am very sensitive to medications. I think Soma helps me a lot, also the L-tryptophan, and Noni juice.

I just came over from the PN board. Started seeing a pain mgmt doc and she put me on Savella. Just like sugar pills! I have SFN and this stuff does nothing for me. I was on 3600mg a day of Nuerontin which worked pretty well, there is no way to get out of all the pain. Maybe it works for FM, but I'm going to cal my doc today and say I want back on the Neurontin. Very little side-effects with it and no weight gain. I have used Neurontin for about 3 years now. Good stuff for me.

But if it works for someone, that's great. We all are trying to find our relief somehow.

I have found Mirapex (a Parkinson's Disease) medication, 4.5 mg or 3 tabs at night to work better than Lyrica. Now, Mirapex is not without side effects but I could not tolerate Lyrica's side effects whatsoever.

Mere

I apologize for double posting. I tend to lose my train of thought (fibrofog I guess). I also wanted to say that my Rheumy told me that the Humira I inject (for my arthritis) also helps FMS. I have found this to be true after having missed a dose.

In support of this statement, Swedish Researchers injected Humira in patients that did not have arthritis but suffered from chronic back pain. Well, it worked in relieving the pain after just one injection. If I remember what he said, apparently, TNF blockers work to balance Substance P (excessive in FMS) and another brain chemical - the name I cannot remember. The drawback = price. Without insurance coverage, Humira costs around $1,000(+) per injection. Injections are 2x per month.

Unfortunately, Humira is not approved for use in controlling the pain of FMS. It should be.

Interesting stuff...

Mere

This is interesting... I wonder if studies are peing done... or if there are drug similarities?