I just wanted to say, I was injured in an accident in 1987. Given a diagnosis of fibro in 1990. I had a clear cut case of Lyme in 1994.

Since 2000 the doctors have argued over my minor salivary lip biopsy, was it Seronegative Sjogren's or not.

In 2004, I discovered I had small fiber neuropathy found on biopsy and autonomic neuroapthy as well.

This year, my nail got ugly and white and lifted totally up off the nail bed. It is not a fungus. It is oncholysis....most often associated with psoriasis. You can get psoriasis in just a nail and have one of the Seronegative Spondyloarthropathies.

Spondyloarthropathies are entheseopathies, or enthesitis....ligament problems, that can feel like arthritis or muscle problems. Of course, every trigger point for fibro is a ligamentous insertion. You could conceivably be diagnosed with fibro, even if it is a spondyloarthropathy. No test will diagnose spondyloarthropathy. You just have to wait until certain things show in your body....waiting, waiting a very long time.

It is very hard to get diagnosed with a seronegative spondyl. If not for this gross fingernail, I would not even bring it up to my doc. Interestingly, some of the drugs used for Sjogren's such as Plaquenil cause psoriasis to manifest. It also explains so many of the huge issues I have dealt with including why I could not tolerate the drugs always given for fibro, such as SSRIs and tricycylics----psoriatic arthropathies come with polymorphisms in the enzyme in the liver that metabolizes these drugs, CYP2D6.

This has been a long and frustrating journey. I still don't know what I have but now it is either seroneg. Sjogren's OR psoriatic spondyloarthropathy or psoriatic arthritis with systemic problems. It will likely take a year to figure out this new development.

I have had to shove abstracts and medical notes under every doctors nose. Then they have the 'Aha' moment. It is frustrating.