I had a lot of problems with my hands and arms going numb. I also have PN in my feet fWIW. I used the wrist braces for about 6 months at night. It really did help and I was surprised that it did, as it was to the point where the pain was so bad that I could not sleep unless sitting up.
After about 6 months I stopped using the braces most nights until I didn't need them at all.
Now I sometimes keep my wrist slightly bent by putting a small pillow under it when I sleep on my side. That helps ease any discomfort.
Turns out I had a herniated disk in my neck that caused the problem even though I was first told it was Thoracic Outlet Syndrome, and then Ulnar nerve entrapment. If not for my family doctor who could read MRI's I probably never would have found out about the herniated disk as the MRI report did not suggest it. And my neck really didn't bother me much.
So to make a long story long, yes the braces really do help!
But I also had an epidural in my spinal column to reduce the inflammation for the disk. That helped a lot but I still needed the braces afterwards.