I recently had an MRI and the results showed microvascular disease. I have been trying to look it up but Iam still not sure what it is. I have to go for more blood work. The techs. that did the MRI are saying it could be from Lyme, lupus (which I was already checked for) or Ms. They feel Ms is the most unlikely. Anyone out there with info. on this, I would greatly appreciate it.
Thanks, Sheila

cadsil disease, a leukodystrophy, is a genetic disease involving the destruction of microscopic vessels deep in the brain. A genetic defect causes the vessel walls to lose integrity and the result is multiple strokes and a lot of brain damage. An MRI does not show the vessel damage, tho, so I don't know what they saw.Cadasil damages can be best seen by an electron microscope at autopsy. The disease is best Dxd by a genetic test. Cadsil is rare affecting 400 families world wide and sysmptoms are migranes and strokes. if you search for "vascular dementia" diseases, I think you'll have better luck getting good information. Good luck.

Thank you for replying. Iam trying to get an appointment with a neurologist. They gave me one for Dec. 12. But since the doctor said my blood vessels are drying up, shinking or what ever Iam pushing for a date, more like yesterday!! Everything I looked up about this seems to lead to diabeites. My sugars were a little high last year but I don't have diabeties. All I know is the MRI, without contrast, showed microvascular disease.

lowering homocysteine levels, C-reactive protein results, and using
fish oil to improve microvascular functioning:

http://www.sciencedirect.com/science...654f019c6ce59a

Thank you Mrs. D for the information on omega 3.

I saw a neurologist that said for someone my age I had too many leisons on by brain. I am 42 years old. The MRI states; multiple few millimeter subcortical areas of T2 hyperintensity in both cerebral hemispheres. The neurologist is sending me for another MRI with contrast and also an MRI of the neck with contrast. The MRI I had done last week suggested that MS should be considered, but there is no involvement of the corpus callosum to suggest MS. My lyme test came back negative as well as the ANA. Has anyone had or heard of someone else haveing a similar experienc? I feel a little like my world is slowly crumbling around me. THis all started because a doctor finaly thought to check my b12 level, which was 209. Now it is 1040 so I guess I can rule out low b12 as the cause of the leisons, or not??

THanks Michael for the info. on CADISAl. If this MRI rules out MS the doctor wants to test my spinal fluid. If that come out negative for MS and Lyme I am going to ask them to look into cadisal.

Hi, I too was diagnosed by MRI with microvascular disease. I had an MRI of the brain with contrast and it showed a 3-4 mm outpouching or bulge as I put it, in the distal and medial carotid artery. It was determined I had mild to moderate microvascular disease on the report. My history is I am 52and postmenopausal. I learned that a decline in estrogen can cause this. My doctor said the MRI showed vascular changes in the brain. Microvascular disease is more about the smaller veins within larger arteries that rupture. My doctor immediately put me on a 325 mg regular strength Bayer aspirin to keep the blood thin. She also referred me to a dietician to help me lose weight which aggravates this condition.