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Old 04-21-2007, 03:42 PM #1
bob26 bob26 is offline
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Default Tyrosine and gluten intolerance

I found this on the MDadvise wed site, has anyone heard of this or had a reaction to tyrosine supplements ? It says allergic not sensitive or intolerant, but.....

Tyrosine
WARNINGS AND PRECAUTIONS

Don't take if you:
# Are allergic to any food protein, such as eggs, milk, wheat.


http://www.mdadvice.com/library/vita/vitamin60.html

Last edited by bob26; 04-21-2007 at 08:12 PM.
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Old 04-21-2007, 06:28 PM #2
KimS KimS is offline
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Great post!

Yes, this relates back to the lectin info. that I had compiled pre-BT-crash. Lectins really kept my attention for about a year because I was convinced that they had something to do with, at least some people's negative experience, regarding gluten and perhaps some other foods.

Honestly, I ran out of subject matter to study and have been waiting for more to arise. Even dieticians and nutritionists that I asked, those years ago, about lectins looked at me blankly while I gave them a quick review. The only way they seem to recognize 'lectins' is if you talk about them in terms of undercooked kidney bean poisoning.

I couldn't read your link but I did make a point of going to find this... which is probably pretty much the same thing.

The glucosamine reference is also very interesting as I've noted many people with gluten intolerance seem to enjoy a better quality of life if they supplement it. I'm not promoting people to run out and buy it. But I am saying that this abstract also creates another line of follow-up that I'm looking forward to exploring!

And with the connection between tyrosine and depression; and gluten and depression, I wonder if this will help to figure out which antidepressants are 'preferable' or 'preferably avoided' with certain individuals based on food sensitivities!

I hope to see more studies directed that way!

http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract

Biochem Biophys Res Commun. 1991 Feb 14;174(3):1154-8. Links
The lectin wheat germ agglutinin induces rapid protein-tyrosine phosphorylation in human platelets.
Department of Biochemistry, Fukui Medical School, Japan.
In response to wheat germ agglutinin (WGA), platelet aggregation and stimulation of protein-tyrosine phosphorylation were observed in a dose dependent manner. These reactions were completely inhibited by coexistence of N-acetyl-D-glucosamine with WGA. Upon stimulation by this agonist, protein-tyrosine phosphorylation of seven bands with molecular masses of 140-, 130-, 80-, 76-, 53-, 38- and 35-kDa proteins was observed by immunoblot. These protein-tyrosine phosphorylations were divided into three groups by kinetics. Considering the previous report from our laboratory that thrombin and collagen induced tyrosine phosphorylation in 135-, 124- and 76-kDa proteins (Nakamura, S. and Yamamura, H. (1989) J. Biol. Chem. 264, 7089-7091.), there may be another signal transduction pathway in tyrosine phosphorylation of human platelets.
PMID: 1996982 [PubMed - indexed for MEDLINE]
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01/02/2002 Even Small Amounts of Gluten Cause Relapse in Children With Celiac Disease (Docguide.com) 12/20/2002 The symptomatic and histologic response to a gf diet with borderline enteropathy (Docguide.com)
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Old 04-21-2007, 07:08 PM #3
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I had trouble with the link, too. I did a search on the site and brought up what I think was the same article about tyrosine you found, bob26. I'll try and copy the link to that, and see if it works. http://www.mdadvice.com/library/vita/vitamin60.html
Good thread, and important info for us. Thanks for the research.
Kim, thanks for your research, too! I'll thank you even more once I figure it out, I'm sure. I'm finding it a little bit dificult at the moment to wrap my 60+ year old brain around all of the scientific jargon. Why can't these scientists talk English?!?
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Old 04-21-2007, 08:23 PM #4
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Thanks Kim and Loisba, I fixed the link, not sure what happened, I couldn't make much of the scientific jargon either, so is it tyrosine bad or tyrosine good ?
The reason I looked this up, I think I had a bad reaction to it, 500mg a day. Actually I think I'm going to do a supplement fast/elimination diet kinda thing to see what I really need.
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