[shomols]

Hi, I just received these test results from the pediatrician and wondered if you could help with them. This is for my son, 16, with Down syndrome.
She said they were a little high but not positive. hmmmm

Celiac EvaluatR W/IgA
IGA Total 140 81-463 range
Tranglut IGA AUTAB <3.0 <4.0

Reference range for Transglutaminase IgA Abs:
less that 4.0 negative
4.0-10.0 Weak Positive
Greater that 10. Positive

Reticulin IGA AutoAB <1:10 <1:10
Endomysial IGA AutoAB <1:10 <1:10
Gliadin IGG AB 13 H <11
Gliadin IGA AB < 3 <11

Please note new reference range 4/05/11
Reference range for Gliadin IgG & IgA Abs:
< 11 Negativve
11-17 Equivocal
> 17 Positive

His thyroid FT4 came back low but she wants to watch that too. I have Hashimoto's so I have that checked every year.

I am so afraid he will have celiac. But he loves his bread which I am sure is a problem.

Thanks so much for your help.

Laurie

[glenntaj]

An isolated positive IgG gliadin is often the first sign of a gluten sensitivity, which is more common than frank celiac.

It does indicate that the body is making antibodies to gluten.

The transglutaminase result is the one most often associated with the villous damage from frank celiac.

It would seem prudent to see if you can get him on a gluten-free diet. Gluten antibodies can have effects well beyond the digestive tract--in fact, Dr. Hadjivassiliou has opined that people with positive IgG gliadin results are more likely to have initial neurological manifestations.

Have you taken a look at Jcc's Gluten File? It's located at the top of this board in the Useful Websites area, and is the best database on the whole subject of gluten out there, and explains this all very well, with references to the actual medical studies and links to the papers.

[shomols]

I looked over so much last night. I will check that again. He is a very picky eater and loves his bread. It will take slowly changing his diet. He has a friend who has celiac and eats a special diet. I know he will probably do okay after the initial fight.
Thanks for your help.

Laurie

Originally Posted by glenntaj

An isolated positive IgG gliadin is often the first sign of a gluten sensitivity, which is more common than frank celiac.

It does indicate that the body is making antibodies to gluten.

The transglutaminase result is the one most often associated with the villous damage from frank celiac.

It would seem prudent to see if you can get him on a gluten-free diet. Gluten antibodies can have effects well beyond the digestive tract--in fact, Dr. Hadjivassiliou has opined that people with positive IgG gliadin results are more likely to have initial neurological manifestations.

Have you taken a look at Jcc's Gluten File? It's located at the top of this board in the Useful Websites area, and is the best database on the whole subject of gluten out there, and explains this all very well, with references to the actual medical studies and links to the papers.

[Jaspar]

There are gluten-free breads. The I know of is Udi's although I personally do not eat it.