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Old 09-28-2006, 10:54 PM #1
annelb annelb is offline
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Default Dr Gluten comes to the US

In Dr. Ford's newsletter he states that he will be speaking at the NASPGHAN meeting. Not sure what meeting as I did not see Dr. Ford's name in the program for the annual meeting in mid Oct.

Quote:
2 - Ford’s gluten-sensitive data in USA
I go to the USA next week. My paper on “Gluten reactions: ten times the celiac problem.”

Here is an early release of the information to be presented at NASPGHAN. Aim: To test if children, with raised gliadin antibodies, respond to a gluten-free diet. Currently, a gluten-free diet is limited to celiac disease. This belief is contested.

Methods: An audit of 921 children referred to a Children’s Gastroenterology and Allergy clinic, over five years (2001-2005). These children were investigated with blood tests for celiac disease with IgG-gliadin antibody (Inova Diagnostics) and tissue transglutaminase (tTG) or endomesial antibody (EMA). Of these, 190 had a small bowel biopsy.

Results: There were 724 with high IgG-gliadin levels (>14 units): mean age 5.3 years, s.d. 3.8. All were offered a gluten-free diet. They were divided into 3 categories:

o 31 children (4.3%) were “Definite celiacs” with histology diagnosis.


o 48 children (6.6%) were deemed “Possible celiacs” because of elevated tTG or EMA antibodies – but with normal small bowel histology.


o 644 children (89.1%), had no evidence of gut damage – labelled “Non-celiacs”.


Clinical features were similar across these three groups, although the “Definite celiacs” had more gut symptoms and fewer food allergies.


Gluten-free outcomes: Of the 644 “Non-celiac” children, 434 trialled a gluten-free diet: of whom 343 (79%) reported substantial improvement. However, when calculated on intention to treat, improvement was seen in 94% of “Definite celiacs”; 75% of “Possible celiacs”; and 53% of “Non-celiacs”. Gluten-sensitivity was seen ten times more frequently than celiac disease: 379 vs 31.

Conclusions: Many children with gastrointestinal and allergy conditions have high IgG-gliadin antibodies. When given a gluten-free diet, the majority got better – they were gluten-sensitive. High IgG-gliadin levels can identify these children.

Gluten-sensitivity occurred ten times the rate of celiac disease.
Dr. Ford's website has a new look: http://www.doctorgluten.com

He mentions Dr. Hadjivassiliou http://www.doctorgluten.com/cms/inde...id=36&Itemid=2

He mentions Dr. Fine http://www.doctorgluten.com/cms/inde...id=60&Itemid=2

Anne
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Old 09-29-2006, 09:48 AM #2
NancyM NancyM is offline
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Wow! Glad to see research like this getting out there. It'll help pave the way for Dr. Fine.
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Old 09-29-2006, 01:37 PM #3
Leslieand Leslieand is offline
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I love it! It validates all of us with intolerance but not celiacs. So, if sensitivity is 10 times more common than celiacs and 4% of diabetics have celiacs that responds to a gf diet, does that mean 40% of diabetics could be gluten sensitive and respond to a gf diet? And for thyroiditis, neuropathy...?
Leslie
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