advertisement
Reply
 
Thread Tools Display Modes
Old 07-27-2015, 10:08 AM #1
Cheryl1818 Cheryl1818 is offline
Junior Member
 
Join Date: Jun 2015
Posts: 82
8 yr Member
Cheryl1818 Cheryl1818 is offline
Junior Member
 
Join Date: Jun 2015
Posts: 82
8 yr Member
Default Need help with lab results

A couple of weeks ago, I saw a new headache specialist who suggested that I try a gluten-free diet. After researching this, I thought I might have Celiac disease based on these symptoms: chronic nausea, abdominal pain, depression, low levels of globulin and total protein, low vitamin D and B-12, unexplained weight loss, headaches, and facial nerve pain.

Before starting the diet, I asked my doctor to test me. The nurse called the next day and said "no evidence of Celiac disease." This morning, they finally posted my lab results online. I'll copy them here-
Immunoglobulin A, QN, Serum (MG/DL) 24 (normal range 91 to 414)
T-Transglutaminase (TTG) IGA (U/ML) <2 (normal range 0-3)

Should I be worried about the low IgA? From what I read online, the low IgA level will skew the TTG result.

If anyone can explain this to me, I would be very grateful. Thanks! Cheryl
Cheryl1818 is offline   Reply With QuoteReply With Quote

advertisement
Old 07-28-2015, 04:05 AM #2
kiwi33's Avatar
kiwi33 kiwi33 is offline
Grand Magnate
 
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
8 yr Member
kiwi33 kiwi33 is offline
Grand Magnate
kiwi33's Avatar
 
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 3,093
8 yr Member
Default

Hi Cheryl

I am an immunologist (among other things) but am not a health professional.

Your low serum IgA might be indicative of coeliac disease but it is not conclusive.

I suggest that you get your care team to check for IgA which is specific for gliadin - this can be diagnostic.

There is more info about this here; https://labtestsonline.org/understan...ease/tab/test/ .

All the best.
__________________
Knowledge is power.
kiwi33 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Cheryl1818 (07-28-2015), DejaVu (07-29-2015)
Old 07-28-2015, 05:59 AM #3
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default And yes--

--low total IgA can skew the results of the anti-transglutaminase IgA test for celiac, most often in a false negative direction.

You may have to go for the gold standard--endoscopic intestinal biopsy to search for atrophied villi. Just make sure it is done at a place familiar with the protocol at which they will take many samples from many different parts of the intestine, not just one of two--especially in the early stages damage from celiac can be patchy.
glenntaj is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Cheryl1818 (07-28-2015), DejaVu (07-29-2015)
Old 07-28-2015, 10:26 AM #4
Cheryl1818 Cheryl1818 is offline
Junior Member
 
Join Date: Jun 2015
Posts: 82
8 yr Member
Cheryl1818 Cheryl1818 is offline
Junior Member
 
Join Date: Jun 2015
Posts: 82
8 yr Member
Default

I know this question has been asked and answered on here before. Thanks to both of you for responding to my question. Both the doctors I have talked to about this seem to think I should forget about testing and just skip straight to going gluten-free. I can't have any more testing right now anyway since I already started eating gluten-free.

Thanks again, Cheryl
Cheryl1818 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
DejaVu (07-29-2015)
Old 07-28-2015, 10:28 AM #5
mrsD's Avatar
mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

I'd really get an endoscope as a last resort. New data is coming out that these scopes are not cleaned properly and spread disease...up to 30% have been found to be contaminated.

And now a "super bug" has been found passed on to 10 patients at a teaching hospital center, from a dirty upper endoscope.

Going gluten free is non-invasive and non drug and much safer IMO. If you Google "contaminated endoscopes" you'll find lots of horrific reports.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
mrsD is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Cheryl1818 (07-28-2015), DejaVu (07-29-2015)
Old 07-29-2015, 10:50 PM #6
DejaVu's Avatar
DejaVu DejaVu is offline
Senior Member
 
Join Date: Apr 2008
Posts: 1,521
15 yr Member
DejaVu DejaVu is offline
Senior Member
DejaVu's Avatar
 
Join Date: Apr 2008
Posts: 1,521
15 yr Member
Heart

MrsD raises a very important point. Please be careful about endoscopies.

Doctors would not believe me, just last Fall, when I was telling them about these dirty scopes. Lol! Where are they getting their info, or are they? We know some are not keeping up with important info.

In addition, endoscopies with anesthesia can cause pneumonia. This includes not only upper endoscopies, but also lower colonoscopies. Heart complications may occur, as well.

People on long-term pain medications often need anesthesia/anesthesiology present during these procedures (while patients not on long-term pain meds do not need anesthesiologists present for colonoscopies).

I see value in simply moving onto the elimination diet.

I hope the diet will help you to feel better, all around.

Warmly,
DejaVu
DejaVu is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
bddouglas (08-03-2015), Cheryl1818 (07-30-2015), mrsD (07-30-2015)
Reply


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
MRI results Blancaboo Multiple Sclerosis 11 08-14-2014 10:59 AM
CT Results + Pic & MRI Results - Thoughts & Interpretation Appreciated OverMyNeck Spinal Disorders & Back Pain 11 04-05-2014 09:35 PM
The results are in.... Someone help! legzzalot Multiple Sclerosis 15 11-18-2008 02:24 AM
Test results in - results given by phone lynxgal Peripheral Neuropathy 3 07-10-2008 05:49 PM
VNG Results, I need help Please Dmom3005 General Health Conditions & Rare Disorders 0 06-25-2007 08:21 PM


All times are GMT -5. The time now is 06:57 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.