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Old 10-03-2006, 08:59 PM #1
annelb annelb is offline
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Default Gluten Neuropathy - Hadjivassiliou

I posted this on BT and it is such a good find I will post it here too. I am confused as to where to post

Dr. Hadjivassiliou does it again. This time an article showing improvement in those who chose a GF diet over those who didn't. The improvement was subjective and objective. These people had circulating antibodies - no reference to biopsy.

Three years ago I stumbled on the PN forum where Cara was posting information about gluten and PN. I feel so lucky that I am gluten sensitive and have had great improvement in my PN by living GF. I hope this article helps more people. I will be sending it to a few doctors I know.
Anne

http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum


Quote:
Muscle Nerve. 2006 Sep 29; [Epub ahead of print] Related Articles, Links

Dietary treatment of gluten neuropathy.

Hadjivassiliou M, Kandler RH, Chattopadhyay AK, Davies-Jones AG, Jarratt JA, Sanders DS, Sharrack B, Grunewald RA.

Department of Neurology, The Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.

We studied the effect of a gluten-free diet in patients with idiopathic sensorimotor axonal neuropathy and circulating antigliadin antibodies. Consecutive patients underwent baseline neurophysiological assessment and were offered a gluten-free diet. Those who went on the diet formed the intention-to-treat group and those who did not were the control group. Repeat neurophysiological assessment and subjective evaluation of neuropathy symptoms were performed at 1 year. A total of 35 patients participated in the study, with 25 patients going on the diet and 10 not doing so. There was a significant difference in the change of sural sensory action potentials (pre-defined primary endpoint), with evidence of improvement in the intention-to-treat group and deterioration in the control group. Subjective change in neuropathy symptoms also showed significant differences, with patients in the intention-to-treat group reporting improvement and those in the control group reporting deterioration. Gluten-free diet may thus be a useful therapeutic intervention for patients with gluten neuropathy. Muscle Nerve, 2006.

PMID: 17013890 [PubMed - as supplied by publisher]

Thought I would add all the articles written by Dr. Hadjivassiliou concerning neurological problems associated with gluten. Thought it might be nice to have a quick reference to all these papers.

Unless there is another M. Hadjivassiliou, he has contributed to 43 papers - these are the ones about gluten.


Neuropathy associated with gluten sensitivity
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Autoantibody targeting of brain and intestinal transglutaminase in gluten ataxia.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum


Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Are lower gastrointestinal investigations necessary in patients with coeliac disease?
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Multiple sclerosis and occult gluten sensitivity
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Making the diagnosis of coeliac disease: is there a role for push enteroscopy?
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

The immunology of gluten sensitivity: beyond the gut.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Gluten sensitivity masquerading as systemic lupus erythematosus
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Choreic syndrome and coeliac disease: a hitherto unrecognised association
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Dietary treatment of gluten ataxia.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

A primary care cross-sectional study of undiagnosed adult coeliac disease
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

The humoral response in the pathogenesis of gluten ataxia
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Gluten sensitivity as a neurological illness.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Headache and CNS white matter abnormalities associated with gluten sensitivity
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Gluten sensitivity: a many headed hydra.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Clinical, radiological, neurophysiological, and neuropathological characteristics of gluten ataxia.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Neuromuscular disorder as a presenting feature of coeliac disease.
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Does cryptic gluten sensitivity play a part in neurological illness?
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Last edited by annelb; 10-04-2006 at 06:50 PM. Reason: fixing broken links
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Old 10-03-2006, 09:20 PM #2
jccgf jccgf is offline
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jccgf jccgf is offline
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Thanks, Anne! I figured out my computer problem, btw, my wireless mouse had a dead battery, therefore my computer appeared frozen.

Cara
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Old 10-03-2006, 09:38 PM #3
annelb annelb is offline
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LOL - I did that once. Problem was that the batteries I put in to replace the dead ones were also dead. I almost bought a new mouse before I tried one more set of batteries.
Anne
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Old 10-04-2006, 06:52 PM #4
annelb annelb is offline
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I am bumping this because I think I fixed all the broken links . If you find that the links are not working for you, let me know.

Thanks for letting me know Claire
Anne
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