PubMed - 2006

jccgf · 12-08-2006, 09:37 AM

Thanks for posting that Nancy! I love that these forward thinking doctors are starting to blog! And this one, in Milwaukee

, just 30 minutes away. I will know who to look for next time I need a cardiologist. I need to have my Vitamin D tested. I hate that many doctors think you are nuts to ask for nutritional deficiency testing.

Cara

NancyM · 12-08-2006, 10:55 AM

That's great, Cara! I've been enjoying his blog.

Well, today by another weird coincidence I turned on the TV and it was on the local university's channel and there was a Internist/Professor giving a lecture on hyperparathyroid. And they did mention how taking too much Vitamin D can cause that, in addition to adenomas.

I'd really love to find out how MUCH vitamin D my body needs because I really don't get any sun, I'm photosensitive from the drugs I take and have really pale skin anyway. But I'm also afraid of over-doing it too.

jccgf · 12-13-2006, 06:45 PM

Celiac Disease and Risk of Liver Disease: A General Population-Based Study. PMID: 17161656 Dec 2006

Quote:

BACKGROUND & AIMS: Celiac disease (CD) is an important cause of hypertransaminasemia. CD might also be associated with severe forms of liver disease. We investigated the risk of liver disease in 13,818 patients with CD (1964-2003) and 66,584 age- and sex-matched reference individuals from a general population cohort. METHODS: We used Cox regression to estimate hazard ratios (HRs) for later liver disease and conditional logistic regression to estimate the risk of CD in individuals with liver disease before study entry. RESULTS: CD was associated with an increased risk of acute hepatitis (HR, 5.21; 95% confidence interval [CI], 1.88-14.40; P = .001), chronic hepatitis (HR, 5.84; 95% CI, 2.89-11.79; P < .001), primary sclerosing cholangitis (HR, 4.46; 95% CI, 2.50-7.98; P < .001), fatty liver (HR, 6.06; 95% CI, 1.35-27.16; P = .018), liver failure (HR, 3.30; 95% CI, 2.22-4.88; P < .001), liver cirrhosis or liver fibrosis (HR, 2.23; 95% CI, 1.34-3.72; P < .001), and primary biliary cirrhosis (HR, 10.16; 95% CI, 2.61-39.49; P < .001). There was no increased risk of liver transplantation (HR, 1.07; 95% CI, 0.12-9.62; P = .954). Adjustment for socioeconomic index or diabetes mellitus had no notable effect on the risk estimates. Prior liver disease was associated with a statistically significant 4-fold to 6-fold increased risk of later CD. CONCLUSION: This study suggests that individuals with CD are at increased risk of both prior and subsequent liver disease.

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