OT - Purple and Blue

LittleMischief · 10-30-2006, 05:15 PM

Beautiful pups (and children, of course).

I am introducing a new food to my allergy prone and hypothyroid Chihuahua, and wondered if anyone had heard of it?

The brand name is Wenaewe.

It claims to be free of: corn, dairy, soy, artificial colors, artificial flavors, wheat, chemical preservatives, by-products, and GM products.

The primary ingredient is organic uruguayan beef.

It contains flaxseed and millet (not so good, really, for hypothyroidism).

Here's the website:
www.wenaewe.com.uy

Anyone heard of this, good or bad?

I'll be checking the dog boards, as well, and will report back if I find anything interesting.

Thanks!

jccgf · 10-30-2006, 06:09 PM

Hi Dottye~

I never heard of that particular food.... so I have no idea if it is good or bad.

The breeder we met has recommended:

Wellness
Chicken Soup for the Puppy Lovers Soul
Natural Balance
California Natural

and cautions to avoid foods that contain wheat, eggs, corn, soy, sugar & dyes.

DogtorJ, a veterinarian with celiac disease, has pet food recommendations on his site: http://www.dogtorj.net/id39.html

Cara

jccgf · 10-30-2006, 06:20 PM

Quote:

Originally Posted by annelb

Have you seen this about food allergies and soft coated wheaten's?
http://www.spinone.com/AKC_CHF99/22FoodAllergies.htm

this one says some wheatens are gluten sensitive. http://consumer.vetmedcenter.com/Bre...aten%20Terrier

You might have already found this ino.
Anne

Anne, we just bought a new book on Wheatens. I don't remember reading this in the ones we got from the library, but perhaps we were guilty of just looking at the pictures...lol.

This one says:

Quote:

Common symptoms of PLE and PLN are vomiting, diarrhea, decreased appetitie, weight loss, fluid retention, and lethargy.

Quote:

Veteranarians should test any Wheaten that exhibits signs of allergies or PLE/PLN. Wheatens that have this disease should be placed on a gluten free (no wheat) diet with a novel protein source such as fish, venison, or other protein source not common in dog foods. Some Wheatens show sensitivity to chicken, corn, and lamb.

So, I wonder how many Wheatens are on a STRICT gluten-free diet from day one, and whether any of those dogs ever develop this? What if people feed their dogs a gluten free dog feed, but then think nothing of giving it a cracker or bit of bread as a snack??

I think the strangest thing is that I didn't know this about this breed going in, but I think maybe it was meant to be

. And how weird is it that two breeds with known gluten intolerance are FROM IRELAND??? (the Irish Setter is another known for wheat sensitivity)

Perhaps the Wheaten Terrier should become the official mascot for Celiac Disease Awareness...lol.

No doggie treats from drive through banking... I guess.

I still haven't talked with DogtorJ...I need to get to that one of these days!

Cara

jccgf · 10-31-2006, 09:32 AM

PubMed on Wheaten Terriers:

Food hypersensitivity reactions in Soft Coated Wheaten Terriers with protein-losing enteropathy or protein-losing nephropathy or both: gastroscopic food sensitivity testing, dietary provocation, and fecal immunoglobulin E.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=10668819

Evaluation of intestinal permeability and gluten sensitivity in Soft-Coated Wheaten Terriers with familial protein-losing enteropathy, protein-losing nephropathy, or both.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=10803646

Familial protein-losing enteropathy and protein-losing nephropathy in Soft Coated Wheaten Terriers: 222 cases (1983-1997).
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=10668820

Intestinal crypt lesions associated with protein-losing enteropathy in the dog.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=10830544

PubMed on Irish Setters:
http://www.ncbi.nlm.nih.gov/entrez/q...uten&db=pubmed

Thank you, Anne, for finding this on the potential use of the zonulin blocking drug being used in veterinary medicine!

http://www.earthtimes.org/articles/s...se,12368.shtml

Quote:

Alba Therapeutics Corporation and The Royal Veterinary College, London Announce Initiation of AT-1001 Study in Patient Dogs with Inflammatory Bowel Disease
Posted on : Mon, 30 Oct 2006 13:08:01 GMT | Author : Alba Therapeutics Corporation
News Category : PressRelease

BALTIMORE and LONDON, Oct. 30 /PRNewswire/ -- Alba Therapeutics Corporation (Alba) and The Royal Veterinary College, London (RVC) today announced that they have initiated a study in dogs stricken with Inflammatory Bowel Disease (IBD), to assess the use of Alba's zonulin receptor antagonist, AT-1001. The double-blinded, placebo-controlled and randomized study will enroll 60 IBD patient dogs presenting to The Queen Mother Hospital for Animals, RVC, in four arms and will assess the ability of AT-1001 to reduce the signs, clinical markers and histopathological lesions associated with IBD.

"We are extremely pleased to be working with the RVC in this important study," stated Dr. Blake Paterson, CEO of Alba Therapeutics. "While Alba continues to assess the use of zonulin antagonist, AT-1001, in validated IBD animal models, the ability to run a clinical trial in patient dogs will provide useful clinical insight and allow us greater confidence that zonulin receptor antagonism may offer advantages over conventional immunosuppressive and dietary measures in both dogs and humans. We are fortunate to be working with our RVC collaborators, as they are uniquely qualified to run this study as established leaders in the development and implementation of animal clinical trials."

Within each of the four arms of the clinical trial, patient dogs will receive a hydrolysed veterinary diet. In the first arm, patients will receive the diet and AT-1001 and in the second arm, patients will receive the diet, AT-1001 and prednisolone. In the third and fourth arms, patients will respectively receive the diet and placebo, or diet, placebo and prednisolone.

"We believe the potential clinical benefit of AT-1001 in diseases characterized by increased intestinal permeability such as IBD to be powerful," stated David Walker, lead Co-Investigator. "Alba's progress with AT-1001 in Celiac Disease, together with the scientific rationale supporting the use of zonulin receptor antagonism in inflammatory diseases, gives us great confidence that this study will open the door to other therapeutic applications for the product," stated Oliver Garden, Principal Investigator of the Canine IBD Clinical Trial.

IBD is an inflammatory disease that can involve either or both the small and large bowel and is often considered a disease of adolescents and young adults, because it is most commonly first diagnosed in people between the ages of 15 and 35 years. Active IBD is characterized by acute inflammation, whereas chronic IBD is characterized by architectural changes of crypt distortion and scarring. Crohn's disease and ulcerative colitis are the best-known forms of IBD. IBD is estimated to affect 1.4 million people in the United States and up to 2.2 million people in Europe.

About Alba: Alba Therapeutics is a Baltimore-based biopharmaceutical company dedicated to commercializing disease-modifying therapeutics and drug delivery adjuvants based on the zonulin pathway. Alba's lead product, AT-1001, is currently in a Phase II trial for Celiac Disease and is planned to enter clinical studies in Type 1 Diabetes in 2007 following an IND filing in late 2006. Alba is testing zonulin receptor antagonists, including AT-1001, in a variety of autoimmune and inflammatory diseases.

About RVC: The Royal Veterinary College (RVC) is the UK's first and largest veterinary school and a College of the University of London. Since its foundation in 1792, it has become a world-leader in veterinary and biomedical teaching and research. The Queen Mother Hospital for Animals is the largest small animal teaching hospital in Europe and leads the world in clinical trials of new and exciting diagnostic modalities and therapeutic agents. The Canine IBD Clinical Trial is being led by Oliver Garden, a veterinarian with over 13 years' experience in the fields of veterinary gastroenterology and immunology.

Alba Therapeutics Corporation

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