My dr said the headache would get a lot worse for about a week or so, mine didn't last that long. I would give anything to be able to get them again, but because I broke out in a rash all over a few hours after the injections there was no way I could get them again. If they helped you, then it might be worth getting them again.

Also as Dr Smith asks, have you tried any anti-seizure meds for migraine prevention? I was on Topamax for years and it did wonders for me, cut down the frequency of my migraines big time!! I was on it so long that the effectiveness wore off.

The best migraine meds I ever took was Amerge. But, as always, I developed an allergy to it.

Amerge (naratriptan) and Maxalt (rizatriptan) are meds in a class called triptans, which are used as abortives in treating migraines & cluster headaches. There are more, but the list is finite, with additions unlikely. As with other medication classes, if one med in the group doesn't work, another med in the same group may work, so "If at first you don't succeed...."

....Another case of trial & error -- taking some time -- in the journey.

Doc

Hey Doc, funny thing is that I tried soooo many migraine meds with no relief (Imitrex, Maxalt, Relpax, Zomig, etc...) Amerge worked the best and I took it for several years, then I had and allergic reaction the last two times I took it

Hmmm. No chance it was something coincidentally concomitant?
How bad was the allergic reaction?

I wonder if one of the others might work for you now...

Doc

Well, my chest got real tight, shortness of breath, a rash, nausea...pretty bad allergic reaction I'd say!

I thought the first reaction might have been a coincidence since I had been taking it so long without issue, but the second time it happened confirmed that it was the Amerge

I have also wondered if the some of the others would help now too...will not try Imitrex again though. The pills and nasal spray did nothing for me and I had a bad reaction to the shots.

I have had the same good experience with Amerge -- every other triptan I have tried makes me feel depressed and only somewhat relieves symptoms, but Amerge (naratriptan) kicks the migraine and makes me feel completely normal. Unfortunately after about 20 years using it, it's not quite as effective as before, but still works in most cases.

Botox was AWFUL -- my head felt bruised for three months and I had a low-level headache all that time as well. The only relief I got was with prednisone. I couldn't wait for it to wear off. And, the doc didn't inject any just above the outside ends of my eyebrows, so when I tried to raise my brows I looked like Jack Nicholson.

And Topamax... blech. Felt awful and didn't help.

I am on 2 different anti seizure meds. I developed epilepsy after 3 surgeries. The meds I take are keppra and vimpat. They have to be brand only because we had a very hard time controlling seizures with generics and other meds. So .. Really there's not much I can do on that end. My epileptologist gave me many different meds and I had a hard time taking all of them. They put me right to sleep, topamax made me feel like a zombie, she gave me some injectable a etc. and when I have a debilitating headache daily, that's not an option. I have been on so many meds and that's why I finally opted for botox. With botox my headaches worsened (a lot!) for at least 3 weeks.

Last time I checked (a few years ago) Topiramate was FDA approved for tx of migraines. I can't stand the med as it causes big time memory issues for me, BUT no doubt it has helped with the frequency of my migraines. It is also now very very rare for me to need the Imitrx shot, which I had to take previously rather often. Now, I take Treximet as an abortive, which has the same ingredient as Imitrex (moderate dosage) and an analgesic. Anyway, Topamax might be something to discuss with your doctor.

I know some people have had some good luck with Botox. Even the ones I know who have gotten some relief, it's been somewhat confusing. I hope your second round of injections works better for you.

I have found keeping my Topamax dosage low, a relatively happy compromise.
I also more and more watch my food intake and have learned better and better ways to manage my stress.

Wishing you well...migraines are a special kind of heartache...but perhaps a special kind of lesson. After almost two decades of this...I'm trying to look at it this way,...not easy.