Reply
 
Thread Tools Display Modes
Old 08-09-2019, 07:54 PM #21
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default Aimovig

On day 35 of the transition from Aimovig to Ajovy. Iím going to try Ajovy for 4 months, then pick what works best.

I have learned the following during my anti-CGRP research on Google and I quote:

Calcitonin gene-related peptide (CGRP) is a vasoactive peptide. It is part of the ďinflammatory soupĒ that is involved in dilation of cerebral and dural blood vessels. Widely distributed throughout the body, CGRP levels in serum increase during migraine or cluster headache. Triptans provide some migraine relief by modulating the CGRP.

CGRP is a neuropeptide that exists in trigeminal ganglia nerves and a potent vasodilator of cerebral blood vessels. CGRP is believed to mediate vasodilatory mechanism of neurogenic inflammation and the transmission of trigeminovascular nociceptive signal from intracranial vessels to central nervous system.

My interpretation and results so far are:

Aimovig and Ajovy work as approved. However, they are complicated drugs.


Sent from my iPhone using Tapatalk

Last edited by godfrey19; 08-09-2019 at 09:06 PM.
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (08-10-2019)
Old 08-12-2019, 09:32 PM #22
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default

Reporting early! On day 40 started getting headaches and decided to inject Ajovy on day 42. I couldnít find any research that supported a 60 day detox from one CGRP med to another. Feeling 100% better. But just day 2 in a CGRP world. Will report back.


Sent from my iPhone using Tapatalk
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (08-13-2019)
Old 08-13-2019, 06:23 AM #23
Wren's Avatar
Wren Wren is offline
Senior Member
 
Join Date: Apr 2007
Posts: 1,388
10 yr Member
Wren Wren is offline
Senior Member
Wren's Avatar
 
Join Date: Apr 2007
Posts: 1,388
10 yr Member
Default

"Triptans provide some migraine relief by modulating the CGRP." I love my Relpax -- my favorite triptan.
__________________
Enemies ..... Don't see them as bad. See them as broken.
Wren is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
godfrey19 (08-13-2019)
Old 08-24-2019, 11:53 AM #24
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default

Been on Ajovy for 14 days. Itís going well. A couple light headaches but minor. Results feel similar to Aimovig 140mg.

I did have a 5 day headache episode while on Aimovig so giving Ajovy a whirl.

Also decided to drop Topamax 50mg as a test. Iíve been on it for 3 years. The Neurologist already knocked it down from 100mg to 50mg. Feel more energetic without the Topamax.

Also after UHC insurance said they wouldnít cover Ajovy I picked up a new prescription for $245, same price as Aimovig. So who knows what happened.




Sent from my iPhone using Tapatalk
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (08-24-2019)
Old 10-02-2019, 10:02 PM #25
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default

Hello!

Met with my Neurologist today. After 2 shots of Ajovy the headache level is similar to Aimovig 140mg. I have light headaches but no migraines on Ajovy. I also stopped taking Topamax.

Originally when we talked about the CGRP options he was very positive about about the results of his patients. This time he was more guarded and stated that the shots along with a secondary drug is working better. We agreed to meet again and recheck how Ajovy is working as a stand-alone drug.

If the headaches start again he suggested taking 25mg of Topamax twice a day. He also was clear that though the CGRP shots are technically safe, itís early in the drugs history.

Take care






Sent from my iPhone using Tapatalk
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (10-03-2019)
Old 10-16-2019, 03:22 PM #26
Wren's Avatar
Wren Wren is offline
Senior Member
 
Join Date: Apr 2007
Posts: 1,388
10 yr Member
Wren Wren is offline
Senior Member
Wren's Avatar
 
Join Date: Apr 2007
Posts: 1,388
10 yr Member
Default

How are you, godfrey? Seems like it's time to hear how you are doing.

I need to hear. This is my third day with a fairly stiff headache and my Relpax hasn't helped at all. Makes me wonder about Aimovig or something.
__________________
Enemies ..... Don't see them as bad. See them as broken.
Wren is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
godfrey19 (10-16-2019)
Old 10-16-2019, 04:37 PM #27
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default

Wren,

Sorry to hear about your headaches and Relpax not working as well. I was never prescribed Relpax.

I took another Ajovy shot on 10/10. Iím still off Topamax. At this point I havenít had a migraine in 2 months. I still get light headaches a couple times a week that can be managed with rubbing Biofreeze gel on the painful spot. I havenít even had to take standard over the counter headache meds.

Like I mentioned before Amovig 140mg and Ajovy both seem to work. However with the Amovig I did get a couple migraines that were painful. Ajovy, at this point, seems to be holding up a little better for me. My Neurologist said that both are good but results very by person.

We all know the pain and trepidation that goes with migraine sufferers. Good luck on your search!

Godfrey


Sent from my iPhone using Tapatalk
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (10-16-2019)
Old 10-31-2019, 02:00 PM #28
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default Aimovig

My dermatologist suggested that I try Botox as an add-on to Amovig. This was based on continued minor headaches in my temple areas and above my eyebrows. He also felt that a little Botox above my eyebrows and the lines next to my eyes would help with my appearance.

I decided to give it a try. After one week the Botox has eliminated the temple and eyebrows headaches. Ajovy is still doing its job as well. However, I have experienced some light headache soreness on my forehead where there is no Botox.

Bottom line, I feel that the Botox addition has been a good and my forehead/eye lines diminished.

Itís a little pricey to do both Ajovy and Botox but after 52 years of chronic migraines Iíll pay the price for now.




Sent from my iPhone using Tapatalk

Last edited by godfrey19; 10-31-2019 at 04:08 PM.
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (10-31-2019)
Old 11-21-2019, 08:41 PM #29
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default

I hope everyone is doing well. With the holidays coming up weíll be facing lots of triggers. This will be my first holiday season on a CGRP med. Actually looking forward to low key gatherings without the fear of a migraine.

All the best[emoji120]








Sent from my iPhone using Tapatalk
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (11-21-2019)
Old 12-14-2019, 08:41 PM #30
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
godfrey19 godfrey19 is offline
Junior Member
 
Join Date: Apr 2019
Location: Long Beat
Posts: 25
1 yr Member
Default

Hello and Happy Holidays!

In my last post I mentioned Botox as an add-on therapy to Ajovy. Bad decision! A couple days after my last post I started getting light headaches in the Botox injection site areas. It lasted for about a week and then went away. I canceled my next Botox appointment. Botox is not for me.

Also my insurance lowered the monthly price of Ajovy to $201 U.S.

The Ajovy is still working well. It is a joy to have reduced headaches during this busy holiday season.

I hope all is well with you. Happy Holidays!

Godfrey


Sent from my iPhone using Tapatalk
godfrey19 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Wren (12-14-2019)
Reply

Tags
aimovig, checking, shot, taking, thereís

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off



All times are GMT -5. The time now is 09:48 PM.

Powered by vBulletin • Copyright ©2000 - 2020, Jelsoft Enterprises Ltd.
Search Engine Optimisation provided by DragonByte SEO v2.0.31 (Lite) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.