HME Ehrlichiosis WITH lyme disease is much worse neurologically than either by itself, as seen in this excerpt from this abstract from pubmed. I had that combo and got really sick fast so that would help explain it!!!
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1: Int J Parasitol. 2006 May 1;36(5):601-5. Epub 2006 Mar 6.

Anaplasma phagocytophilum-infected neutrophils enhance transmigration of Borrelia burgdorferi across the human blood brain barrier in vitro.

Nyarko E, Grab DJ, Dumler JS.
Division of Infectious Diseases, Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

More B. burgdorferi crossed both human BMEC and EA.hy926 cells in the presence of A. phagocytophilum-infected neutrophils than with uninfected neutrophils without affecting endothelial cell integrity. Such a mechanism may contribute to increased blood and tissue spirochete loads.

PMID: 16600247
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

and here you see how truly NEURO sick it can make you!!!!
EXCERPT

1: Clin Vaccine Immunol. 2007 Nov;14(11):1420-4. Epub 2007 Sep 26. Links

Anaplasma phagocytophilum-Borrelia burgdorferi coinfection enhances chemokine, cytokine, and matrix metalloprotease expression by human brain microvascular endothelial cells.


Grab DJ, Nyarko E, Barat NC, Nikolskaia OV, Dumler JS.
Department of Pediatrics, Johns Hopkins University School of Medicine, 200 North Wolfe Street, Room 3147, Baltimore, MD 21287, USA. dgrab@jhmi.edu

(this coinfection) enhanced or synergistically increased production of MMPs (MMP-1, -3, -7, -8, and -9), cytokines (interleukin 6 [IL-6], IL-10, and tumor necrosis factor alpha), and chemokines (IL-8 and macrophage inflammatory protein 1alpha) known to affect vascular permeability and inflammatory responses.

PMID: 17898182
http://www.ncbi.nlm.nih.gov/pubmed/1...RVAbstractPlus

yet there is no reliable testing for erhlica? (sp?)

thanks in andvance

derek

Nice to see you here*)*)!!

There IS no reliable testing for Ehrlichiosis. It is a real shame.

There are 4 kinds of human pathogenic Ehrlichia in the USA, but the most common are HME and HGE. Yet even tests for those are so flawed that they can completely miss fatal, acute cases. Here is an abstract documenting 4 fatal, acute cases of Ehrlichiosis, 2 of which were blood NEGATIVE. Blood negative Ehrlichiosis has been documented repetitively from all over the world where it occurs.

QUOTE:
Evidence of E. chaffeensis via IHC, ISH, and PCR was documented in all 4 cases. Abundant immunostaining and in situ nucleic acid hybridization were observed in spleen and lymph node from all 4 patients.

Significantly, in 2 of these patients, serologic evidence of infection was absent.

UNQUOTE
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum


And here is a reference regarding 4 species of Ehrlichia human pathogenic in the USA. http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Ehrlichiosis can kill very quickly and unfortunately, it has this past year killed 2very young people in the same state, Missouri.

It killed Emily Powell, 15, in just a couple of weeks, and killed Ellen Cary, 7, in just 10 days... It can kill very young, very healthy people, like Erin Zinna, 19, a boxing champion, who died in seven days exactly.
http://home.swbell.net/dsny1fan/zinna.html is her tribute page.

All of those girls died of Ehrlichiosis in MISSOURI.

Erin Zinna, 19,
Emily Powell, 15,
Ellen Cary, 7.

All very healthy before, all died within 2 weeks!!!

Ehrlichiosis can manifest with fever & flu-like symptoms.
It can manifest as IBS or as TTP.

ALL OF THOSE LOVELY YOUNG PEOPLE COULD HAVE BEEN SAVED WITH
ORAL DOXYCYCLINE!!! A study on RMSF therapy has shown that short-term Doxy won't mess up kids bones and it ok for emergencies like these.

Tragically, Ehrlichiosis is both one of the most lethal TBDs and one of the most EASILY TREATABLE. It is easier to eradicate than almost any other TBD.

Just oral Doxycycline.