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Old 02-25-2011, 02:59 AM #1
72daywmn 72daywmn is offline
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Default Morphine?

Today I went to see my new doctor, establishing him officially as my "pain management" doctor and 'authorized treating physician' for work comp.
In the beginning, I was very impressed with his listening skills, and bedside manner, as he seemed to understand my concerns, and was quite compassionate about my pain levels.
The fact that I used and brought in a pain journal I printed out from the American Pain Foundation (Thanks a board member here- though I forget exactly who- thanks, though!!) helped a great deal.

He explained how my hydrocodone was a short acting med and that it was inappropriate for my long term chronic pain condition, and pointed out, without me saying it, how my life is/ has been dominated by my pain levels and the medication for it- needing to take a pill every few hours and then wait for it to kick in to allow 1-2 hours max each day of decent pain control...

So, he had me sign a pain contract, which I have NO problem with at all, and prescribes me Morphine 15mg extended release tabs twice a day, 12 hrs apart, and Ultram 50mg twice a day for the breakthrough...He compared my 7.5/500 hydrocodones 5x daily to this morphine dose, and said he expected it to be better than my current pain control without the peaks and valleys.
And I was ecstatic! I thought finally I'd get some relief!

BUT THEN>>>>> total letdown....
My last hyrdrocodone was taken at about 2:30pm, about an hour before my appt.- I was hoping to not hurt too terribly bad if he needed to poke and prod and stretch me around in exam...The pharmacist said to go ahead and start the morphine tonight, and usually my daily hours are sleeping from 6am to Noon-ish, and I am awake from Noon to 4am ish- the two hours from 4am-6am are generally spent fighting in my chair or my bed on the floor to get comfortable and pain reduced enough to sleep...
Anyway, so I was at about a 9/10 pain wise by 9pm, so I went ahead and took the morphine, figuring I'd get up again at 9am to take the next dose...but NOTHING. My pain did not go down AT ALL. Not a half a step. NOTHING.
I took an Ultram and two tylenol to give it a boost around 10:30pm and the pain went down to an 8/10...but thats where I stayed. Now it's almost 2am, and its going back up to 9/10. I signed this stupid pain contract promising that I would not take anything other than this that he gave me, and I don't want to screw this up because I think he will genuinely help me deal with this...but there is no one I can call, and nothing I can do through the night but suffer. (And vent to everyone here. )

My next dose of morphine should be at 9am, and the doctors office opens at 8, but idk if I'll be awake then...hopefully not!
Does anyone know about morphine dosing? From what I have read online, this 15mg is the lowest dose- is it pretty common? Is there some sort of conversion ratio between the hydrocodone and the morphine? Do I need to give it time to build up in my system? And is it ever going to work better than it is now????
It feels like I haven't taken anything- it is not even touching the pain at all, let alone relieving it. HELP???
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Old 02-25-2011, 05:42 AM #2
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Funny you should bring this question up. I'm going through something similar. I have different symptoms and a different diagnosis, but (now I'm not a doctor nor do I play one on t.v.) I really think a great deal hinges on just exactly what your issues are. Morphine for me has been less than effective as well and I'm eager to get back to my doctor on the 7th to see what we can do. I do know that morphine is for pain, and if you have any kind of nerve issue then it really won't help much. There may be other problems that morphine, as a pain killer, simply won't help. If I'm able to find out anything further I'll let you know. In the interim, don't hesitate to contact your doctor if something isn't working...because there's probably a good reason why it isn't! Fingers crossed for you and best of luck to all of us.
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Old 02-25-2011, 06:52 AM #3
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Lightbulb

Morphine takes a little longer to get going, because of its liver metabolism etc.

Give it 2 to 3 days before reporting to doctor. But you might need an increase or adjustment.
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Old 02-25-2011, 09:06 AM #4
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Originally Posted by mrsD View Post
Morphine takes a little longer to get going, because of its liver metabolism etc.

Give it 2 to 3 days before reporting to doctor. But you might need an increase or adjustment.
Hi 72daywmn,

What she said. Morphine is one of those that has to build up in your system; hang in there!

There are conversion guidelines (websites), BUT I hate to utilize them for the simple fact that they aren't really relevant, as illustrated by those who report that one opioid doesn't work at all, but another (of "equivalent" dosage) works great. Guidelines are just that; every drug needs to be titrated independently to find the correct dosage for the patient.

Here are a couple posted here a few years ago:
http://www.globalrph.com/narcotic.cgi
http://www.mywhatever.com/cifwriter/...y/70/4932.html

Doc
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Old 02-25-2011, 12:56 PM #5
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Hi 72daywmn,

What she said. Morphine is one of those that has to build up in your system; hang in there!

There are conversion guidelines (websites), BUT I hate to utilize them for the simple fact that they aren't really relevant, as illustrated by those who report that one opioid doesn't work at all, but another (of "equivalent" dosage) works great. Guidelines are just that; every drug needs to be titrated independently to find the correct dosage for the patient.

Here are a couple posted here a few years ago:
http://www.globalrph.com/narcotic.cgi
http://www.mywhatever.com/cifwriter/...y/70/4932.html

Doc
Thanks for the help everyone!

UPDATE- It's working, it's working!!! Imagine my surprise and relief this morning when I woke up fairly early- which in itself is a miracle for me - to take my second dose of Morphine, and exactly one hour later I was nearly pain free!!!
3 hours after the second dose, the pain is not totally gone, because I can feel the "zaps" but they are seriously muted, and the hard, excruciating ache is more an uncomfortable ache than the kind that would normally bring me to tears. I am seriously amazed! I just hope it lasts the 12 hours it's supposed to!
So far, the only side effect is a slightly elevated heart rate and blood pressure, for which my regular Lisinopril should do the trick.
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Old 02-25-2011, 09:18 PM #6
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Unhappy Help!!!

Ok, well the pain control lasted until about 3:00pm- so roughly 6 hours after the second dose, and the pain's been climbing since. I took 4 tylenol and a tramadol as I was supposed to for breakthrough pain, but its nowhere near helping. My next dose is at 9pm, and tomorrow is my son's 14th birthday, so I've got a cake to make and laundry to be done and UGH!

I'm in a small rural town and no way contact the doc until Monday- don't want to violate m pain contract but don't want to ruin my boy's b-day being in agony all day and unable to do anything with or for him either...

Does anyone know how particular doctors can be about pain contracts? Especially when they've just begun? If I take my hydrocodone as needed for BT pain over the weekend and am totally honest with the dr on Monday about it, is this going to screw everything up??? I've tried everything I can think of to avoid it, but can't stand this pain, and the only other option is to look up the dr's home address and number, which seems really desperate and ridiculous in a way, but what else is a girl to do?
HELP!
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Old 02-25-2011, 10:14 PM #7
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Originally Posted by 72daywmn View Post
I'm in a small rural town and no way contact the doc until Monday- don't want to violate m pain contract but don't want to ruin my boy's b-day being in agony all day and unable to do anything with or for him either...
Speaking as one raised by a single parent disabled w/ chronic pain, your son will understand.

Quote:
Does anyone know how particular doctors can be about pain contracts? Especially when they've just begun?
I wish I could answer that for you. You did get some relief from the last one you took, and since they're 12 hrs apart, you won't really be going through the whole weekend like this. 12 hrs. - one pill - at a time; try to give them a chance to build up like they're supposed to, and by all means contact your Doc Monday morning if things don't get better.

Doc
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Old 02-26-2011, 12:51 PM #8
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Unhappy

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Originally Posted by Dr. Smith View Post
Speaking as one raised by a single parent disabled w/ chronic pain, your son will understand.



I wish I could answer that for you. You did get some relief from the last one you took, and since they're 12 hrs apart, you won't really be going through the whole weekend like this. 12 hrs. - one pill - at a time; try to give them a chance to build up like they're supposed to, and by all means contact your Doc Monday morning if things don't get better.

Doc
Thanks Doc, for your encouragement! You were right, my son does/did understand- today's his birthday, and I was beating myself up over not being able to take him anywhere because I hurt too bad to leave my chair, but he says he's rather just hang out in his room and play his pc and xbox games with his 'adopted' brother and order pizza. (He's 14, so that's like a dream! lol) so tragedy averted there! Phew~


Unfortunately, we're on day two- took the third dose last night, and fourth this morning, and I'm miserable. Of course, I don't know quite how to explain it to the doc Monday morning, but I'm thinking that in general, the baseline med is close to ok- could be a little stronger if that's what it would take to last longer as an extended release, but most importantly, my breakthrough pain is unbelievable. I thought I had so many high and lows with the hydrocodone because of the way it would wear off and I'd have to wait for another pill to kick in, but with this, it's like there's never any 'kicking in' and the breakthrough is more noticeable. :'(

The doc had said on Thursday that he appreciated my pain journal, so I'm just tryin to keep track in it still where my pain levels are, and I'll go see him on Monday. So far, I did end up taking one more Tramadol than I was *supposed to* last night just to get some rest, I figured that's what he told me to use for BT pain, so one extra might be more ok than taking something else not on the plan, and I took four tylenol and four advil before getting to bed finally at 6am- but I've resolved myself that I am NOT going to take any of the hydrocodone, no matter what, unless he tells me to use that for the BT. It occurred to me last night that some of the pain I'm having now could be a physical withdrawal from the hydrocodone I've been on for 30 months- know anything about that?

Well, fingers crossed that the morphine will 'build up' enough as you say to do some good!

Thanks all for the support
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Old 02-26-2011, 03:53 PM #9
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I don't know quite how to explain it to the doc Monday morning
Google: how talk doctor pain

It's all there. Talk about your pain and its effect on your day-to-day life - levels, location(s), type/description of pain, etc. Show him your journal if he wants to see it - he may or may not. Don't push it. Let him make the decision about how to adjust your meds. Titrating can take a little time; it will be worth it. The two things to keep in mind are:

1. The goal is not to be pain-free; the goal is to reduce the sense of suffering and improve the quality of life.
2. To find/use the least amount of medication necessary to achieve the desired result.

Quote:
It occurred to me last night that some of the pain I'm having now could be a physical withdrawal from the hydrocodone I've been on for 30 months- know anything about that?
It's very possible and not unlikely. It's known as rebound or rebound effect. It should dissipate as your body adjusts to the new meds.
http://en.wikipedia.org/wiki/Rebound_effect
http://www.merriam-webster.com/medlineplus/rebound

Doc
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Old 02-26-2011, 03:58 PM #10
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Basically the long acting products with opiates do not last what they say they will. I wouldn't expect a 12 hr. release. Neither does your doctor. Hence he gave you breakthru meds.

The next size up is 30mg/tablet for this product.

Give it two more days, to reach steady-state. If you don't see any improvement by then start your pain journal again.
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