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Old 10-23-2011, 05:31 PM #1
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Default Gabapentin and weight gain

Hi there, is it common to gain weight extremely quickly on this drug? Dose increased approx 2 weeks ago to 900mg x 3 daily and feeling really bloated and probably gaining more pounds as I type, no change to diet and no appetite increase that I've noticed
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Old 10-23-2011, 11:03 PM #2
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Originally Posted by Lindyloo View Post
Hi there, is it common to gain weight extremely quickly on this drug? Dose increased approx 2 weeks ago to 900mg x 3 daily and feeling really bloated and probably gaining more pounds as I type, no change to diet and no appetite increase that I've noticed
My mother has been on this and gained weight also. She felt hungry and ate frequently and more than she previously had. When she changed to Lyrica she did not have as much of a problem. Everyone responds differently however. Hope this helps.
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Old 10-24-2011, 09:31 AM #3
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Originally Posted by Lindyloo View Post
Hi there, is it common to gain weight extremely quickly on this drug?
It's common; I don't know about the "extremely quickly" part.
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Neurontin and Weight Gain

Several side effects are possible with Neurontin, and weight gain has been reported. It appears more frequently in children than in adults and can often be combated by eating heart-healthy foods and exercising regularly. However, if you experience a rapid weight gain, you should report this to your healthcare provider, as it may be a sign of a serious medical condition.
http://epilepsy.emedtv.com/neurontin...ight-gain.html
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Old 10-24-2011, 12:00 PM #4
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Everyone I know who has taken gabapentin/neurontin has experienced some weight gain. I think it's more common when you first start the drug.

I gained 4 pounds the first month and I was only on 1200 daily, but I haven't gained anything in the past 5 months.

I wonder if the weight will come off when I finally stop the drug.
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Old 10-24-2011, 02:11 PM #5
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I wonder if the weight will come off when I finally stop the drug.
It's supposed to, but of course you'll have to do your part.

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Old 10-25-2011, 10:49 AM #6
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Thanks for all replies, will try to keep a check on food intake maybe I'm 'forgetting' the odd cake or too!
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Old 10-25-2011, 10:52 AM #7
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People who gain rapid weight, within days, not weeks...typically are holding fluid (water weight).

Watch your salt intake, and have your kidney functions checked often, because this drug is excreted whole by the kidney with little if any metabolism by the liver. This may strain some patients who have marginal kidney activity.
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Old 12-16-2011, 08:12 PM #8
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I know subject well, and have had mixed results?

I began Gabapentin Jan. 2008 - at the time weighed 170, a good age/frame/height appropriate weight for me. I took 1800 mg/day for years, last year 2400 mg/day.

4 years later, I weigh about 45 pounds more, which I am not too thrilled about, especially considering the very 'minor' relief I receive from the drug.

I've found that IF I try really hard to eat less/correctly and/or exercise within my limitations, I can lose weight, albeit much slower than ANY time before the drug.

But to be fair, I do NOT attribute ALL of this weight to gabapentin! How much I cannot really say, maybe about 15 lbs? I also attribute about 15 or MORE lbs. to just not being as active as I was before these problems. And at least 15 or so from too much 'comfort' eating.

Everyone is different, so mileage may vary. A conscientious MD will certainly help you monitor weight fluctuations so you can make informed decisions.

That being told, I to look to titrate down and find another med soon...mostly for poor quality of relief.

JB
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Old 12-16-2011, 08:51 PM #9
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Yes - I stopped taking Gabapentin a long time ago for that reason. All I could think of was food and that never happened to me in my life before. My appetite was unbelievable. As soon as I stopped the med, the appetite went back to normal!
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Old 12-17-2011, 11:13 AM #10
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Originally Posted by ms er since '06 View Post
All I could think of was food and that never happened to me in my life before. My appetite was unbelievable.
You sure that was gabby and not MMJ?

I kid to break tension/stress, but it's unfortunate considering the relief MMJ is giving to so many MS sufferers.

Best wishes & Happy Holidays,

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