I just have to point out.... that solvents like ACETONE do not
exist in the human body. They are poisons. http://www.nlm.nih.gov/medlineplus/e...cle/002480.htm What you see in a little cup from 4 tablets reacting to acetone is not applicable to what happens in your GI tract. There are many many drugs that use polymer systems for sustained release. One is Concerta , for children. Some are heart pills, like ProCardia. Here is an article explaining these hydrophilic matrices: http://www.colorcon.com/literature/m...PTEarticle.pdf While the change in OxyContin is real, and does affect patients, because the release rate is perhaps slower than the OC version.... It is certainly not poisonous or harmful because of the matrix chosen. There is a post in the stickies here for reporting drug reactions to the FDA Medwatch: http://neurotalk.psychcentral.com/thread2864.html |
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I plan to move in a few months to a larger area, namely Spokane, Washington, and will have access to better medical care, which it sounds like I will need! Thank you again! MissTT |
I Know Why the OP's Made You Sick
I too had a terrible reaction to the new "OP" Oxycontin formula. It caused me severe abdominal pain, especially on my right side. Also, it took at least 90 minutes to start working, but once it did, I felt extremely dizzy--as if the whole dose released all at once instead of gradually. Anyway, out of sheer frustration, I started researching and was shocked at what I found out. You see, as part of this new "tamper-proof technology," in addition to the "glue-like" stuff, a MUCOUS MEMBRANE IRRITANT is added, which is intended to cause pain in the nasal passages if the drug is snorted. Didn't they care that the intestines and bladder are also lined by mucous membrane! It's no wonder we have abdominal and bladder pain after taking the "OP" formulation!!! If you want to do some research on your own, here's a web site for to a company called Acura that has developed, trademarked and patented their "Aversion Technology."
*edit* You can dig a little deeper by looking up their patent application on the U. S. gov. patent office web site and reading their submission. This is SO wrong, in so many ways, to those of us who live in constant pain. Anyway, at least now you know why the "OP" formula gave you bladder pain. Sending e-HUGS to you and everyone else who needs one. :) |
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I don't doubt that some people are suffering the side effects described here; that's not at issue. I don't know exactly what's causing them, or why, but if it is these inactive ingredients, there appears to be some sensitivity at work that effects only a small minority of patients. MANY complain that the OP formulation does not work as well as the old OC formulation, which is resulting in either doctors prescribing higher dosages and patients paying more for them, or patients suffering with inadequate pain control. However only a small minority are experiencing these extreme side effects; most patients are not. I'll reiterate, these side effects should be reported to the appropriate entities (specified elsewhere in this thread) and alternative medications prescribed. Different people have different sensitivities to different medications all the time, and alternatives have to be found. Doc |
You are entitled to give your point of view, but please don't discount mine. I've done my homework too.
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I know exactly what you are talking about here. I was doing great for years on OC. these new op have been increasingly making me sick. I have been lethargic and have had abdominal pain and bloody stools. I have also experienced the gel like substance these monsters turn into. Its like a combo of rubber cement and super sticky super glue. I mean, it if you touch it, it will stick to your hands and turn into stringy, super sticky strands of gel that you cant wash off. YOu literally have to peel and rub it off with something dry. It really is something you have to experience firsthand to understand where we are coming from. After experiencing it, you will realize that it simply can not be good for our systems to have this stuff in it. And its not like our bodies are breaking this stuff down into something non harmful. Our digestive systems are mostly water. Stick one of these pills in water for a few hours, and it still turns into one of these gel blobs. It is sad that the small percentage of ppl who abuse these meds are making our lives miserable. Us chronic pain patients are the ONLY ones being harmed by these reformulations and cracking down on supply. God forbid when the day comes when we cant get our IR meds anymore. Like this poster, nothign else works for my pain like oxycodone. FEntanyl works well, but the patches are a problem within themselves. I could bet that purdue did not do proper human testing into how these new ingredients effect our bodies longterm. I am on a very high dose compared to the average patient, and therefore have been cramming more of this crap into my system for the past two years. The ONLY way we could ever get anyone to listen is simply to band our voices together. Altogether, there are nearly 100million ppl in the US suffering from chronic pain. A large percentage of us are on pain meds. Even if a few million of us get together, which isnt really asking alot, who could afford to ignore us? My only hope now is that the FDA allows generic versions of the original oc formula to be made come aprl 2013, although i think im farting in the wind with that hope. |
Wish I'd known, when I came off of 12 hour release OxyContin and the liquid form for breakthrough pain, I took them all (sealed) back to the pharmacy who THREW them away as even though I'd not opened them, the had to do.
Would much rather have sent them out to someone. |
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You did the right thing by turning them in. ;) Doc |
It seems the OP is no longer posting. However, I will throw out this idea anyway. I think her digestive tract is screwed up. She appears to be absorbing things oddly. Would suggest diet clean up. ?taking antacids? Perhaps defeating the appropriate break down of this med. Good luck.
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