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Old 02-14-2013, 07:23 PM #1
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Default Amantadine experience anyone

The neurologist I saw is recommending a titration of amantadine up to 400mg for me to my pain (regular) doctor. This sounds scary to me as I have had problems with medication. I am sensitive. Has anyone taken or does take this? Is it helping? What is it helping with? What are the side effects? Thanks for any guidance. Also, I have liver dysfunction. Is this hard on liver? Happy valentines day everyone. Hope you are all having a good day. Love to you all.
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Had MVA in 2006 resulting in post concussive syndrome manifested by cognitive impairment, chronic pain/ fatigue. Chronic pain of head, neck, back, left leg.
Other problems include REM sleep behavior disorder, nocturnal frontal lobe epilepsy, chronic migraines associated with nausea/vertigo, episodes of passing out, hypoglycemia, liver dysfunction (had accidental overdose of acetaminophen in 2009) had liver and kidney failure, hernia, degenerative disc disease with compression of nerve root, PTSD, and other problems associated with functioning problems from traumatic brain injury (light, sound sensitive, easily overloaded, easily distracted, cannot focus, anxiety problems etc.)
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Old 02-20-2013, 11:58 PM #2
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Default

amantadine is an anti viral used for the flu so I am curious how it would pertain to pain?
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Old 02-21-2013, 11:27 AM #3
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Lightbulb

Amantidine is a NMDA receptor antagonist. NMDA receptor is a pain trigger.

Here is an article on the various drugs tried to block this function:

http://www.uspharmacist.com/content/.../1500/c/28282/

Memantine is Namenda, and some posters on RSD have used it or are using it now.
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Old 02-21-2013, 07:28 PM #4
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Default Amantadine for traumatic brain injury

Sorry, I was not clear on my post. The amantadine is supposed to improve cognitive function after traumatic brain injury. Has anyone tried it for this? What were the results?
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Had MVA in 2006 resulting in post concussive syndrome manifested by cognitive impairment, chronic pain/ fatigue. Chronic pain of head, neck, back, left leg.
Other problems include REM sleep behavior disorder, nocturnal frontal lobe epilepsy, chronic migraines associated with nausea/vertigo, episodes of passing out, hypoglycemia, liver dysfunction (had accidental overdose of acetaminophen in 2009) had liver and kidney failure, hernia, degenerative disc disease with compression of nerve root, PTSD, and other problems associated with functioning problems from traumatic brain injury (light, sound sensitive, easily overloaded, easily distracted, cannot focus, anxiety problems etc.)
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Old 02-22-2013, 11:08 PM #5
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Sounds interesting. Learn something new every day. I'll be following this post.
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Old 04-09-2013, 07:32 AM #6
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Default it works

I have been taking 100 mg Amantadine every morning for the last six months.
You are lucky to have found a doctor who understands what living with a brain injury incurs.

It has increased my alertness, spacial awareness and cognitive functions better than any other drug I have taken over the last eighteen years.

My advice is, try it at a low dose, 100mg is the lowest, and you will know within five days if it works for you.

After eighteen years of avoiding noisy stimulating environments, I can now sit back in a relaxed state taking it all in with no indications of confusion and fatigue. It works for a few hours of exposure and if necessary I would take another 100mg. I find I would rather leave than to take anymore tablets if it is possible, because of the perceived long term side effects.

After six months, I have no side effects and 100mg is just as effective as when I started but the thought of doing more, by taking more, is tempting but I have avoided the challenge.

It does not do much for your memory, you are not going to be back to you once were, it will not repair damage, it just allows you to live a better life in the present.
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