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Old 02-19-2016, 11:25 AM #1
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Lightbulb Acute delerium may occur with antibiotic treatments:

This is an important finding IMO:

http://psychcentral.com/news/2016/02...ion/99349.html
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Old 02-19-2016, 05:41 PM #2
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MrsD - I just read this article and was about to forward it to you as I thought it might interest you but then I saw your thread and that you were onto it already.

Let's hope they follow through with the suggested additional research - who knows they may finally make the connection between antibiotics and PN and draw some much needed attention to that subject.
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Old 02-20-2016, 08:39 AM #3
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Lightbulb

Let me expand on this delirium topic a bit.

Cipro and other fluoroquinolones have been known to enter the brain since they were approved by the FDA. They had a warning for the elderly who seem to have this problem more than younger patients, to be given lower doses for treatments.

The elderly also get a form of delirium from H2 antagonists. (like Zantac and Pepcid).

Today the data bases for pharmacies also flag anticholinergic drugs for the elderly.

But I was surprised to see penicillin listed on that article as a potential culprit!
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Old 02-20-2016, 03:32 PM #4
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I was surprised by penicillin as well.

It seems that it and other beta-lactams can have neurological effects, apparently mediated by effects on GABA neurotransmission.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175508/
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Old 02-20-2016, 04:09 PM #5
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Well, that's just great isn't it.

When my son was diagnosed, erroneously I believe, with Sydenham's Chorea at age 5 he was promptly placed on Penicillin. I was told at that time he would need to be on it until he was in his 20s. Penicillin was used as a prophylactic treatment to prevent future episodes of Rheumatic Fever. It still is I have read.

By the time he was 10 and after years of my pleading that they were "wrong!" he received differential diagnoses so was subsequently taken off the Penicillin.

So basically they were treating an autoimmune condition that affects movement, mood/behaviour and possible heart involvement with something that can possibly (emphasis on possibly) cause all the same symptoms and more except for the heart involvement.

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