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Old 03-03-2016, 09:45 AM #10
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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In short.... The MTHFR mutation affects B12 as well as folate.

If you are not methylating B12 then you do not have active working B12. Taking high dose (and you are taking mega high dose) methylfolate and NO B12 to balance it, will lead to neurological damage.

This is why Deplin is an RX item to prevent people from misusing it.

https://umm.edu/health/medical/altme...-b12-cobalamin

do you know your B12 level? Many doctors still do not know that 400pg/ml is the new acceptable low for B12.

Did you check the links I gave you? Doing your own supplementing of Bcomplex, methylfolate and methylB12
can cost only about $40 for 3 months supply...and you are paying more than that for one month?

I would suggest you supplement AT LEAST the methylB12 yourself. It must be taken on an empty stomach for best absorption. It will only cost you pennies a day.
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