Hi,
I took Risperdal (4 mg for one week, 2 mg for some weeks and 3 mg for three days) from early August to early September 2016.

This drug has damaged the Basal Ganglia of my brain, because I have cognitive impairment and anhedonia.

I wanted to ask: is there a way to "repair" the basal ganglia?

Hi RisperMan

Welcome to NeuroTalk - I hope that you find the community as knowledgeable and supportive as I have.

Have you discussed the things that you are experiencing with the doctor who prescribed Risperdal?

It could be that they are short-term effects of your brief use of Risperdal which will resolve with time.

Also, what you are experiencing does not necessarily reflect damage to your basal ganglia.

Your prescribing doctor should be able to discuss these things with you and (depending) suggest further investigations/options.

All the best.

I am no longer followed by my prescribing doctor. Actually I'm going to sue him.

What procedures were used to diagnose your possible basal ganglia damage?

Are you currently seeing another doctor about your health issues?

I've seen an endocrinologist and he confirmed my problems are due to Risperdal.

Basal Ganglia damage cannot be diagnosed because there are no tests that could monitor the chemical imbalance of the brain.

I've come to the conclusion that my Basal Ganglia are damaged after knowing Risperdal affects them and they control learning, emotions, cognition and motivation, all of them have decreased after I took Risperdal so it's quite obvious my Basal Ganglia are damaged

The basal ganglia complex has been implicated in many neurological processes but it is not functionally nor anatomically independent of the rest of the brain.

Parkinson's Disease has been directly linked to damage to the substantia nigra which is part of the basal ganglia complex. Similarly, Huntington's Disease has been directly linked to damage to the striatum which is also part of the basal ganglia complex.

I don't know of any other neurological disorders which have been directly linked to damage of any specific part of the basal ganglia complex.

What about dyskinesia?

Dyskinesia is a possible side-effect of taking Risperdal but as far as I know its anatomical/physiological basis is poorly understood.

You might find the information here helpful in this context Risperdal - FDA prescribing information, side effects and uses.

Hi Risperman, I didn't take Risperdal, but I know what it's like to have damage to the Basal Ganglia. My damage is in my hypothalamus gland. It's a very important part of the B.G. They can see a 5 mm lesion at the entrance to my pituitary stalk, but the neurosurgeon wouldn't tell me about it, so he said, "Your MRI results aren't back yet, but I'm sure you didn't have a stroke." I had an adverse reaction to an RX drug, called Gabapentin / Neurontin. Back to your question. Can they repair the Basal Ganglia? I really don't think so. Maybe time will slowly fix your problems, by rewiring. These stupid drugs can cause more harm than good. Sorry about your problems.