Hi everyone
I had been taking Lyrica since around feb/march of this year.
I had been feeling better than i had in a VERY long time!
About 4-5 weeks ago my feet started hurting,so of course i took my socks and checked them out.I couldn't even see my ankle bone!
I was also having lower back problems,so i thought i should go get checked out.
I was told my liver enzymes were raised and to stop taking the Lyrica!
I have been inMISERY ever since.
I feel like i had when all this first started 3-4 yrs ago!!
I hurt all day long!!!!
My feet are still retaining fluid,but not as bad.
I was wondering if anyone here had experienced this,also how long before it can possibly clear up?
I wasn't put on water pills or anything.I'm basically being shuffled between 2 docs that seem fed up with me!!
So nothing has been done yet.I really wanna go back on the Lyrica,but they say wait,even though nothing is being done about the retention.
I am going to see a neurosurgeon on the 11th.I guess they are hopin he will take over!
Fed up with doctors...Kell

It is excreted whole in the urine. 90% I could not find anything in the literature on liver effects.

Edema is common with it however.
You can have pain and aching with edema.

Hi Kell-
I was wondering if you had ever tried neurontin, topamax, or zonegran? If you are being prescribed the lyrica for pain, these other meds have similar modes of action, being that they all increase the levels of GABA in the CNS. And PNS for that matter! My fav amongst all of these is probably topamax- I've had the least side effects on that one. I've switched through all of these over the years trying to find the least side effects and least grogginess. Maybe one of these could be a replacement for the lyrica with fewer problems.

Linnie

Thank you for your replies!
I have tried it all Lynn!!
This one worked the absolute best for my nerve pain..
I'm gonna try taking water pills/with potassium..Once i have the ok from one of my docs...
Have a good week<3
Kell

Kell,
I am suffering from fluid retention in my legs and it's probably from my Lyrica. To combat this, my rheumie put me on Lasic every other day and it's a small dose. He has me eat a banana every night too.

Billye

Lasix depletes THIAMINE.... which can lead to more edema (a vicious circle) and other unsavory effects.

So make sure you are taking at least a B-50 complex with it. Or thiamine alone.
This is not expensive and will save you much grief.

(this happened to me).

Kelley I had to stop Lyrica last week due to terrible swelling too. I am so sad to see it go, due to pain issues and yet my mind is so much clearer, and my leg stopped hurting. I still have some slight swelling in my left ankle and am sure it will go away soon.
I think one of my best bets is to try and lose my excessive weight. UCK! I know it is not the whole answer, yet know that it sure would help with trying to drag around a painful body, wearing plus sizes. Gaye

I agree with the b complex and would also suggest lemon juice in water with honey to taste... For Mom I use one tablespoon lemon juice to 8 oz of water...

I am currently on a very very low dose of Lyrica cousin Neurontin( 100mg) and I have been doing the lemon juice..

as for liver enzymes raising doesnt surprise me but I would think the kidneys would be the strain if 90% is urinated out... the 10 might not metabolize right in the liver causeing the upped enzymes... no fun I have to deal with Liver issues with my dog

When I was still on Lyrica I suffered from various side effects. The worst were weight gain, bloating & swelling. After I stopped taking Lyrica those side effects slowly went away.

thanks Mrs. D.
I somehow missed your answer to this. I've added thiamine to my daily supplements now.

Billye