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Medications & Treatments For discussion about medications and treatments for any disease or health condition, including issues of medication toxicity. |
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10-21-2006, 06:25 PM | #1 | ||
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>>Neurotin clearance does depend on good kidney functions.
hmm.. i forgot about it. it'll depend on the clearance of the rest of the drugs, though.. (to be at risk, I mean). >>And chronic use of NSAIDs can affect the kidney, negatively. what do you mean "negatively"? and thanks for the links! I'll do my homework soon. But here's some references I have: Depakote and naproxen (or ibuprofen): in vitro studies show that naproxen could displace valproic acid from its plasma protein binding site, thus increase the free conc. of valproic acid (Dasgulta abd Volk 1996) and as we talked about, INH does increase depakote plasma concentration resulting in clinically significant intoxication (Jonville et al., 1991) one day I hope I'll do my homework properly.. |
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