Quote:
Originally Posted by mrsD
I see by the drug list you posted, Mickey, that you may have bipolar disorder.
There are standard drug engines on the net, which you can plug in your drugs and read potential issues. I have some listed in the stickies here.
While hydrocodone may cause increased sedation, or cognitive impairment mixed with other drugs that also share that side effect, there is another potential reason for affecting you.
http://neurotalk.psychcentral.com/thread54633.html
It has been known for a while that some people with OCD or refractory depressions react favorably to opiates. This is not well understood yet, but involves the mu receptors in the brain. Opiates vary also in this effect. For example, some opiates, (oxycodone more so than others) also release serotonin in the brain, which is similar in action to antidepressants.
Here is a drug checker with the lithium/ibuprofen interaction explained:
http://www.drugdigest.org/DD/Interac...22+&CheckFDA=1
When using this checker, there is no interaction (classically known) between lithium and hydrocodone/acetaminophen products (like Vicodin/Lortab)
This does not mean there may not be one, only that there is no documented evidence thus far.
Not all doctors know about opiates and bipolar however.
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Thanks for all the information. I do use ibuprofen for milder headaches and pains and not one doctor ever told me in eleven years about that interaction. I have had lithium toxicity before, and at the time they could not explain it, but I never would have dreamed that ibuprofen may have been the cause. Thanks for all the information, you probably saved me from another trip to the hospital with toxicity issues