Hi! I have benign fasciculation syndrome (riny muscle twitches everywhere, triggered by anxiety especially - my neuro who is the chief of neurology at a top Boston hospital told me this literally is another manifestation of migraine, so FYI there). I also am 8 months post-concussion and have post-concussive syndrome or PCS (lots of migraines, fatigue, etc.). Anyway, amitriptyline is prescribed to treat PCS but only works in 70% of people. It is a tri-cyclic anti-depressant (TCA) administered at a very low dose. It not only didn't work for me to treat my PCS, but it induced neck spasms for me after a few days of taking it, and they never went away. it's been months now. The same neuro doc put me on clonazepam. My advice to you is that if you have a tendency to develop myoclonic jerks (like me), AVOID drugs that have a likelihood of giving those side effects. Even avoid drugs in the same class as those that have that myoclonic effect. You are more sensitive and therefore prone to developing them. I have TMJ issues from my concussion and my TMJ doctor prescribed flexeril, which is also a tri-cyclic anti-depressant (TCA). It CAN cause muscle spasms, dystonia, etc., too, since it's a TCA, so I basically decided against it and stuck with the clonazepam I'm already on.

My bottom line: If you have a tendency toward muscle spasms, avoid all drugs that have those side effects, because your symptoms could turn into more permanent spasms, dystonia, torticollis, etc. I can't post links as I'm a new user *edit*

Hugs!!