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03-29-2010, 07:04 AM | #1 | |||
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Magnate
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Seattle, WA (PRWEB) March 29, 2010 -- Kineta, Inc. announced today receipt of a Phase 1 Small Business Innovation Research (SBIR) grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH). Awarded under the NIAID’s expanded Phase 1 program, the $600,000, two-year grant will help finance IND-enabling studies of ShK-186, Kineta’s first-in-class therapeutic for type 1 diabetes mellitus, multiple sclerosis and other autoimmune diseases. The award includes a subcontract to George Chandy, M.D., Ph.D. of the University of California at Irvine for mechanistic studies
Read more: http://www.earthtimes.org/articles/s...#ixzz0jZ9vRz5F ************************************************** * This is the drug that I have been studying since a month after being diagnosed with MS. It is the only drug that has made any sense to me. It is FINALLY going to human trials later this year! And the good news is I have a neuro appt next Monday, I have been hounding her to keep updated on this therapy. It is the potassium channel blockade that makes blocks certain T cells from activating. It has been proven to work in MS along with RA, and a few other autoimmune diseases. And at last check it was available in a pill form. I will be emailing Dr Chandy again today to see if I may qualify for this study. Problem is, it is in California and I am in Virginia, so I may have to talk my neuro into getting on the band wagin with this one. And even if I am not in on this study, I am SOOOOOOO excited that this has finally made it to human trials!!
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"Thanks for this!" says: | Aarcyn (03-29-2010), barb02 (03-29-2010), Dejibo (03-29-2010), ewizabeth (03-29-2010), Grammie 2 3 (03-29-2010), karousel (03-29-2010), Twinkletoes (03-29-2010) |
03-29-2010, 07:53 AM | #2 | |||
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Grand Magnate
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Isn't Amphry (Fampridine renamed) a potassium blocker also? If you get in, tell us about it!!
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03-29-2010, 12:37 PM | #3 | |||
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In Remembrance
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More poison????
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03-29-2010, 02:25 PM | #4 | |||
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Magnate
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LOL more poison indeed. Actually, Ty is a potassium blocker also. BUT, the new poison hasn't caused anyone to get PML yet.
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"Thanks for this!" says: | SallyC (03-29-2010) |
03-29-2010, 05:49 PM | #5 | |||
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Member
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Pretty sure the rep for Fampridine said potassium escapes the damaged area and Famp does "something" about it? I dont remember. Which makes you wonder..does Famp do more then increase endurance possibly heal? Thanks for the heads up legz. Find out. I see my neuro mid April and Ty isnt doing any miracles for me.
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"Thanks for this!" says: | legzzalot (03-29-2010) |
03-29-2010, 08:16 PM | #6 | |||
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Magnate
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Eddie, from what i understand, when the particular T cells activate, there is a reaction where calcium activates the potassium channel causing the cell to kind of wake up and get moving. What they have discovered is that if you block the calcium or the potassium the cell cannot activate both elements have to be present for the cell to respond.
I remember reading some studies being done to block the calcium channel which worked great for shutting down the cells...but of course meant less calcium for your bones and teeth, and of course osteoporosis and other problems. The reason I like this particular study is because it is the same group of people who discovered that the same type of cells that eat myelin are the same type of cells that cause RA, Diabetes, and I think it was Krohn's disease. (Been 2 yrs since I found the first documentary, which I cannot find now.) It is really fascinating stuff, and I cannot wait for more information to be available that is easier to read.
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