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Old 11-28-2010, 09:56 PM #1
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Default MRI, with or with contrast.......

Is an MRI of brain without contrast sufficient enough to dx. late onset MS, or is contrast needed?

I also had a spinal tap......negative, but I have read that one can still have MS with a negative spinal tap.

My doc said "You do not have MS." How can he say that if these tests are not concrete tests for MS???!!

I wish I could believe him, but how can I?

What is the deciding factor?
Confusion keeps creeping in......
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Old 11-28-2010, 11:51 PM #2
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from what i understand, you have to have the bands in your cerebral-spinal fluid (csf) or its not MS. but it could be a sneaky bastid, i dunno. heres to hoping you can get a solid diagnosis asap

i am just a noob at all this so dont take my word for it
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Old 11-29-2010, 07:59 AM #3
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You CAN have a negative spinal tap and still have MS.

You do not need contrast on a MRI to diagnosis MS, Contrast shows new lesions that are between 30-45 days new....but all lesions will show on a non-contrast MRI, the doctor just will not know if the are new.

I had my initial MRI with contrast....but I refuse to anymore, I don't want that toxin in my body, I have enough to deal with.

Hope that helps. Also, your doctor is looking at your clinical symptoms and your neuro exam in combination with all these test. MS is a Clinical diagnosis.
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Old 11-29-2010, 08:03 AM #4
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Banding isn't present in everyone's spinal fluid that goes on to be diagnosed with MS, nor do all neurologists test for it.

With that said, a positive MRI isn't present in every MS diagnosis.

If you have an MRI that's a positive and fits within the criteria otherwise for MS (for example), the spinal is sometimes avoided all together.

I'm sure quite a few folks here will tell you they never had a spinal.
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Old 11-29-2010, 08:20 AM #5
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If you are not in an active or "flare" phase of the disease, most Spinal taps are negative. We throw those Obands when we are eating our own mylin.

MS has been dxd many times based on symptoms (sx) alone, with and without MRI studies. The contrast will only show "active" lesions or will cause active lesions to light up.

MS is a frustrating dx for so many. You can be left on limbo island for years while chasing that rabbit.

I would find an MS center for a more reliable dx.
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Old 11-29-2010, 01:08 PM #6
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i was diagnosed (dx'd) without a spinal tap, however, i did end up having O-bands. i had sx's (symptoms), an abnormal neuro exam and lesions shown on MRI.

you might want to consider a 2nd opinion.
it can take time to dx MS. lesions may not show up for several yrs depending on your condition, any flares etc.

did your dr try to rule other diseases by exam or labwork?
MS can mimic other illnesses.

keep a sx journal. if you develop other sx's it may help your dr follow your history. keep sx's and dates in a little notepad.
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Old 11-29-2010, 02:54 PM #7
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Was your MRI positive or negative?

Approximately 5-10 percent of those with MS have a negative Lumbar Puncture (LP)/(spinal tap).

There is a criteria for diagnosing MS (McDonald Criteria).
Here is some information about diagnosing MS:
http://www.nationalmssociety.org/abo...-ms/index.aspx
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Old 11-30-2010, 12:23 PM #8
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Red face My brain MRI without contrast was neg.....

Quote:
Originally Posted by Snoopy View Post
Was your MRI positive or negative?

Approximately 5-10 percent of those with MS have a negative Lumbar Puncture (LP)/(spinal tap).

There is a criteria for diagnosing MS (McDonald Criteria).
Here is some information about diagnosing MS:
http://www.nationalmssociety.org/abo...-ms/index.aspx
according to neuro - Report says small white matter lesion within the right frontoparietal operculum and within the white matter of the left parietal lobe. Says likely age related.

My spinal tap and clinical observation in office were neg.

Do lesions have to be in certain areas of brain to be MS specific?
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Old 11-30-2010, 01:21 PM #9
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I'm not sure of the answer about brain lesions. Maybe this thread will help:
http://neurotalk.psychcentral.com/sh...ons#post212996
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Old 12-01-2010, 08:58 PM #10
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The CSF can show several things that are indicative of MS (and considered in conjunction with other testing).

I have MS but did NOT have oligoclonal bands even in the midst of my first flair. But I did have high IgG Index and IgG Synthesis in my spinal fluid.

My doc. also did a visual evoked potentials test because there was some question in the beginning as to whether I had MS due to a long running fever. The visual evoked potentials was on the border of abnormal in my left eye which showed a slight delay. Combined with the MRI that had enhanced and non-enhanced lesions, the high IgG Index and Synthesis, they concluded MS.

NurseNancy is right--keeping a symptom journal is a good idea!
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