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Old 04-26-2011, 06:00 PM #11
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Quote:
Originally Posted by Harry Z View Post
No wanting to sound pessimistic, but can anyone name one successful treatment that worked on that poor MS mouse that eventually proved beneficial to MS patients?

Harry
Ahhh, to be a mouse.
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Old 04-26-2011, 11:25 PM #12
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Kicker, you dont want to be a mouse (for one, they're gross! EWWWWW!!!)

They GAVE that poor mouse MS. Torturing that nasty little piece of vermin (better him than us!) but after they do all their tests on those mice, they do little mouse autopsies to see what all their experiments to them. (they dont wait for the mouse to die a "natural" death either. They help them along in that regard)

Nope, I'd rather be the human benefiting from the mouse being experimented on. Hopefully we get to benefit from it.
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Old 04-27-2011, 06:27 AM #13
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Erin, TMI, TMI!!!! EEEEWWWW.

I once had a very psychotic student. He would start conversations with me "You of the species that lives in the boiler room". Always thought he meant mouse or rat. He called his psychologist (one of the nicest ladies ever) "the Evil One". Even the other students thought him "odd".
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Old 04-27-2011, 09:16 AM #14
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Their 7 year time line is highly optimistic. It has usually been 20 or more years and most treatments that help the mice don't work for humans.

And, the mice don't have MS, they have EAE which mimics MS for research study.
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Old 04-27-2011, 12:22 PM #15
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Poor little Mousey Guys.....for naught..
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Old 04-27-2011, 01:28 PM #16
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Why didn't this make front page news in the USA?
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Old 04-28-2011, 08:06 PM #17
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Quote:
Originally Posted by karilann View Post
Why didn't this make front page news in the USA?
Because this country -----'s nowadays. The holy FDA has to hug, kiss, embrace, profit, ect. We'll stop getting loans one day. That week, things will change.
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Old 05-09-2011, 03:33 AM #18
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I'm one of those who think MS has more than one cause. Some may be cured by one thing, and someone else may need something else. MS is a cluster of diseases.
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Old 05-14-2011, 01:52 AM #19
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You've got to take all of these early reports of major advancements in the fight against MS with several large grains of salt. More often than not these releases are meant to kickstart funding for the research, or to increase the stock prices of the companies involved in the initial research.

Sorry if that's a jaded view, but it's the doggone truth. You must keep in mind that mice simply do not get MS. They are given a disease that mimics MS by injecting the mice with myelin proteins, to which they have an allergic reaction. This allergic reaction causes their immune systems to attack their CNS, but that's as far as the similarities between the mouse disease (EAE) and human MS go.

As others have noted, even if this research did prove effective once transitioned to humans, you're looking at a minimum of seven to 10 years before it hits the market.

Sorry to be a downer, but I find it almost unconscionable the way the emotions of MS patients are played with by these hyped up stories of "major discoveries" that are never heard from again…

The medical research model that has evolved in the last couple of decades is seriously broken. Desperately ill patients have been transformed into consumers, and that's a very bad development…
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Old 05-14-2011, 06:50 AM #20
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My sodium level is so elevated by all these reports, it can only be a bad thing. I can't wait until they start using sexy, happy women on commercials to sell MS drugs!
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