I've been taking Astaxanthin (4 mg) daily. Would taking this as well as Prodantim be overkill? I also take Krill Oil but that is more for my heart health than an antioxidant dosage.

I'm not sure Kelly.

Protandim has:

Milk thistle extract (Silybum marianum) (seed)
Bacopa extract (Bacopa monnieri) (aerial part)
Ashwagandha (Withania somnifera) (root)
Green tea extract (Camellia sinensis) (leaf)
Turmeric extract (Curcuma longa) (rhizome)

They don't say how much of each of these is in it. As with all things, there are benefits and side effects. And some of these can't be mixed with medications, like green tea. If you are on a blood thinner, you should not drink/take green tea. I have also heard that green tea and ADs are not a good combination (I can't remember why). So, like anything, it's best to double check with your dr. or pharmacist before adding to your medications.

The ingredients are exactly:
Milk thistle (Silybum marianum) extract (225 mg)
Bacopa (Bacopa monniera) extract (150 mg)
Ashwagandha (Withania somnifera) root (150 mg)
Green tea (Camellia sinensis) extract (75 mg)
Turmeric (Curcuma Ionga) extract (75 mg)

Its a synergistic formula, so the ratios have to be close for it to work (per Dr McCord - the scientist who formulated it). There is a peer reviewed study on the subject too (the synergistic effect). Dr McCord claims that individually each ingredient doesn't really work. He used the its ability to stimulate Nrf2 (the protein that regulates the DNA antioxidant response), as the measuring stick.

*edit*

Astaxanthin doesn't interact with Protandim... the only thing the manufacturer says to not take it with, is if your on auto-immune suppressant drugs (like you had a kidney transplant). Protandim will up your immune response, so we don't want you to lose the kidney.. if that makes sense.