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Old 12-03-2011, 07:47 AM #6
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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This is the official reason for the interaction:

http://www.drugs.com/interactions-ch...5-360,1115-648

SSRI drugs also increase bleeding risk:

This is another search using Lexapro as a substitute:
http://www.drugs.com/interactions-ch...13-565,705-360

It explains the bleeding risks.

Wellbutrin may be an option for you since it does not affect serotonin. However, metabolism of Wellbutrin is affected, so lower doses may be used. (but the doctor may refuse to give this anyway with the interaction):

http://www.drugs.com/interactions-ch...05-360,440-203

So 3 separate reasons for 3 separate antidepressants combined with Plavix.

Tapering down with Prozac takes time, since it is a long acting drug in the body. Some doctors allow tryptophan OTC to help with this. But I don't know if that will affect the Plavix as well.
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