hi lisa,
i'm also sorry you're going thru so much. unfortunately meds are tough. so much of it is trial and error and up/down with doses. then, when you're on so many it's difficult.

the main thing is that you have a good pcp (hopefully an internist) that listen to you, believes you and validates you. then you have a team approach (with you as the leader) that can work.

do you have a neurologist? did you have an mri? do you have any positive tests for MS?

i'm on a lot of meds also. i'm also on a pain med and my pain dr does random urine tests. that's typical of what drs do when giving pain meds. they know you're a legit pt and not abusing.

i hope your dr can tease apart what will help you the most.

Thank you everyone for your thoughtful responses! I am so grateful to have a platform to come and talk about all of this with people that understand what I'm going through. It has helped me so much! Hope you are all well today and hugging your loved ones tight after all of the senseless violence going on this week

Sorry to hear what you're going through. I also have the same symptoms, have taken the same meds that you are taking, also with no luck. The only thing that's worked for me is Requip (or Ropinirole) for spasms. For nerve pain, sometimes I use over the counter Neuragen from the diabetic section at Walgreens. Hope this helps. Nora

Dear Lisa, Its a long time since your original post but.....if you are still struggling i wanted to share some thoughts. I also have a high heart rate same bpm and chronic pain sufferers often have that. With all those meds and no relief I think a visit to a pain clinic is in order. Never heard of Cymbalta being given for nerve pain. Its hard on your liver. I am on some of the same meds for pain and spasticity - 2mg of tizantidine 2x per day,40 baclofen,40 oxy,but i have hit a wall and even botox injections don't help so i did baclofen pump trial-it worked. Thats my next step and you may want to look into that

Hope you find relief!

Melanie