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-   -   Evaluating Risk versus Benefit of Drugs for MS (https://www.neurotalk.org/multiple-sclerosis/2333-evaluating-risk-versus-benefit-drugs-ms.html)

deb46 10-02-2006 09:31 PM

Thanks for posting this link. Like you I have had some bad experiences with Avonex. My doctors keep telling me I need to get back on something but I have this deep gut feeling that keeps telling me NO. My experiences with my deep gut feelings during my life usually turns out to be right so I keep telling the doctors NO!

Cherie 10-02-2006 09:51 PM

I can look back at the last 10 years and see 5 of decline and 2 of Avonex and monthly steroids and feeling pretty crappy and not getting much better, then 3 and a half years on Rebif and getting better and better and better. I'd never have believed it possible 5 years ago that i could have recovered as much lost ground as I have especially with that horrendous foot injury thrown in the mix.

My recommendation: If you've only tried one thing and it hasn't worked, give one of the others a go. There's a good chance you'll hit on something that works for you.

Harry Z 10-02-2006 10:41 PM

Quote:

Conclusion: Given the difference in baseline risk and severity levels across studies, ARR is the appropriate way to compare DMDs in the absence of head-to-head clinical trials. Results based on ARR showed that IFNB-1a sc has comparable therapeutic effect on efficacy measures when compared to natalizumab.
I'm sure when the insurance companies' docs read this kind of report, they aren't exactly going to be eager in recommending that Tysabri be covered without a lot of red tape.

Harry


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