After the miserable fail of Copaxone, my neurologist and I sat down and discussed treatment options yesterday. I had had an allergic reaction to Copaxone in July after 5 injections, my neurologist ordered me to stop them. We discussed Tecfidera, but my neurologist decided against it since I already have chronic nausea. He ruled out Extavia because of the injection frequency. We settled on Plegridy since it is a single injection every 14 days. I am very sensitive to medications, at least that's what they tell me...lol... I was hoping someone may have tried Plegridy and could give a little insight.