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-   -   Covid-19 Vaccine (https://www.neurotalk.org/multiple-sclerosis/256190-covid-19-vaccine.html)

kiwi33 11-23-2020 08:23 PM

Jesxes, I hope that your PhD work goes well :).

The data for the Oxford/Zeneca Covid-19 vaccine is complicated. It is based on a modified form of a chimp common cold virus and its protective effect ranges of 70% to 90% depending on the details of the dose.

The Moderna vaccine, based on mRNA, is more complicated.

agate 11-28-2020 05:08 PM

I found this:

Quote:

Vaccination against COVID-19 and the use of DMT in MS: future scenarios

A huge effort for the development of a vaccine against COVID-19 is ongoing worldwide, whose discussion in deeper detail is outside the scope of the present review.59 When safe and effective vaccination will be made available at the public, subjects at risk, included those affected by chronic diseases such as MS, should be given priority access. However, depending on the type of vaccine and on the ongoing DMT, not all MS patients will likely be immediately eligible. For instance, live attenuated vaccines are contraindicated during treatment with many DMTs.60 Moreover, several treatments affect the response to vaccination, particularly anti-CD20 drugs, but also fingolimod,61 with mixed evidence on natalizumab.When an inactivated vaccine will be available, strategies will have to be implemented, including, for instance, temporary de-escalation of MS patients to treatments that affect the response to vaccination less.
It is part of this article from Multiple Sclerosis Journal (November 18, 2020), "COVID-19 in patients with multiple sclerosis undergoing disease-modifying treatments":

SAGE Journals: Your gateway to world-class journal research

agate 01-16-2021 02:33 AM

National MS Society guidance on COVID-19 vaccine for people with MS
 
The National MS Society has published "COVID-19 Vaccine Guidance for People Living with MS" (January 13, 2021):

COVID-19 Vaccine Guidance for People Living with MS | National MS Society | National Multiple Sclerosis Society

This part of the article discusses the specific MS drugs that may need some adjustment in dosage scheduling in connection with the administration of the vaccine:

Quote:

Based on data from previous studies of other vaccines and DMTs, getting the COVID-19 vaccine while on any DMT is safe. Some DMTs may make the vaccine less effective but it will still provide some protection. For those taking Kesimpta, Lemtrada, Mavenclad, Ocrevus, or Rituxan—you may need to coordinate the timing of your vaccine with the timing of your DMT dose. Work with your MS healthcare provider to determine the best schedule for you. We are in the process of developing considerations for providers to use when making these decisions with you.

Atticus 01-16-2021 03:21 AM

I am likely to be offered the vaccine in the next week or so, as I work in front line healthcare. I've got a history of peripheral neuropathy and genuinely fear those symptoms coming back permanently as a result of a vaccine.

I appreciate the following is anecdotal evidence and not scientific evidence but in the real world that's what helps inform decisions.

Four close friends have had covid 19. Two of them are clinically obese and diabetic but described the symptoms as "bad flu." All 4 have made full recoveries. Several other locals I know of have had covid. None of them went to hospital. All, as far as I know, are well. The survival rate of covid is 99%

So is Covid more dangerous than the vaccine? Does PN or whatever draws you to this site count as an underlying condition?

I'd be interested in your thoughts.

agate 01-16-2021 12:15 PM

I'm sure that COVID-19 is more dangerous than the vaccine. Like any new vaccine this one has its risks but great strides seem to have been made in the world of vaccines in recent years, and the medical profession is really favoring the COVID-19 vaccines even though they are new and approved faster than usual due to the COVID situation.

COVID-19 is very risky for older people and for those at high risk for other reasons.

A neighbor down the hall has a chronic neurological disorder that is very disabling. She is bed-ridden. She got COVID from one of her helpers but so far hasn't been feeling very badly and hasn't been hospitalized. She's in her 60s or 70s too.

Yes, lucky people get milder cases of it. But there are all too many very unlucky people who can die of it. More than for flu, for instance. This article is from WebMD:

COVID Far More Lethal Than Flu, Data Shows



I'm drawn to this site because I have MS--as well as PN due to Type 2 diabetes. Type 2 diabetes is considered an "underlying condition" that puts a person at greater risk of severe COVID-19 though MS isn't one of those conditions so far as I can figure out.

caroline2 01-16-2021 12:58 PM

Reading this again and I don't have MS but due to my sister's condition and MS, I know enough about it. Personally and I still believe it's been so rushed and the distribution of it is a big MESS and the Covid virus, I've read and heard from so many on the many degrees of this virus, from no issues and death...and of course we need to remember that so many that we're told have died did have a lot of other chronic health issues....

And again keeping one's immune system strong regardless of health issues, Vit C, D, Zinc, Quercetin and as I've said plenty times here I believe the Grape Seed Extract I take for decades keep me healthy and proud to say 82 yrs young...

My 50cents today...

kiwi33 01-16-2021 05:22 PM

Caroline which parts of the immune system do you mean?

The cells of the immune system include memory T cells, effector T cells, memory B cells, effector B cells, among others.

All are important in vaccines for Covid-19.

I know of no immunologist who recommends supplements for a strong (whatever that means) immune system

caroline2 01-16-2021 06:41 PM

I mean primarily the Respiratory system mostly and for me my Vit C, D, Zinc, Quercetin and Grape Seed Extract keep this SYSTEM of my body in tip top condition. I have NO respiratory issues and at 82 I'm a happy person. And I know MANY MD's who preach the above for their strong good health and I could post many of them here but I don't think they are wanted here. But maybe I'll post a list of Alternative MD's in the Vitamin/Supplement section that some members may appreciate. **

The two things that seem to stand out with this Covid is respiratory and the smell/taste and I have both as I sit here and eat a great reuben sandwich.

And Kiwi I know you and I come from opposite ways of healing and I'll embrace pharma and I take a couple meds but very little. And I've been in the ER from a pharma drug back in the 80's, so this was my
beginning of where I am now.

Jomar 01-16-2021 07:19 PM

Quote:

Originally Posted by jesxes (Post 1290561)
Hello All,

I would like to know if anyone has received advice about the incoming coronavirus vaccines, if your neuro has recommended to take it, or to avoid it...?

I just had the flu vaccine this month and all run ok , but I understand that covid vaccines are much more experimental.
The main risk I suppose it's the vaccine generating a cold/influenza with fever that may trigger a flare-up.

If someone knows of any official statement about the vaccine to MS patients, whether its from the Mayo clinic, the NHS, MS Society, etc..please post it here!


Please stay on topic vaccine relating to MS , neuro recommended or not..

Atticus 01-17-2021 04:43 PM

Quote:

Originally Posted by agate (Post 1291481)
I'm sure that COVID-19 is more dangerous than the vaccine. Like any new vaccine this one has its risks but great strides seem to have been made in the world of vaccines in recent years, and the medical profession is really favoring the COVID-19 vaccines even though they are new and approved faster than usual due to the COVID situation.

COVID-19 is very risky for older people and for those at high risk for other reasons.

A neighbor down the hall has a chronic neurological disorder that is very disabling. She is bed-ridden. She got COVID from one of her helpers but so far hasn't been feeling very badly and hasn't been hospitalized. She's in her 60s or 70s too.

Yes, lucky people get milder cases of it. But there are all too many very unlucky people who can die of it. More than for flu, for instance. This article is from WebMD:

COVID Far More Lethal Than Flu, Data Shows



I'm drawn to this site because I have MS--as well as PN due to Type 2 diabetes. Type 2 diabetes is considered an "underlying condition" that puts a person at greater risk of severe COVID-19 though MS isn't one of those conditions so far as I can figure out.

Hi Agate,

Thanks for your thoughtful reply. I have decided to go ahead with the vaccine. I havent been offered one yet but have responded to a request for details. No medical history has been requested. I will report back my experience.
Thanks again,
Atty.


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