The package insert identifying liver damage as a risk to Crohn's patients has been in place since January 2008. This new warning expands the area of concern to MS patients receiving Tysabri, doesn't it?

From what I gather, liver damage with Tysabri has been openly discussed since the latter part of 2007. I have to assume it's on the radar longer than that... It also appears the damage can happen at any time during treatment (which is also the case with the inteferons, I experienced that ) but that it can be rather severe and fast moving so hopefully, this will lead to more aggressive testing for liver damage.

Don't get me wrong - I love that Tysabri is an option for all of us - me included, even though I'm not considering it at present - but it's no silver bullet and it does come with a set of risks. Those risks are ever evolving and I think it's fair to be able to discuss them freely and honestly.
becca44