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-   -   another round......... (https://www.neurotalk.org/multiple-sclerosis/39690-round.html)

Bannet 02-25-2008 08:09 AM

Hi Kay. Sorry you are not feeling well:hug: Hopefully the roids will kick in fast and the swelling will go down.

Like other people have already said, Mobic is a anti-inflammatory. Everyone is different though.

It may help you where with others it doesn't. Let us know how its working for you.

Hope you are better by the time company comes.

babs954 02-25-2008 01:38 PM

Kay,
Sorry you are not feeling well. You wouldn't by any chance be on Rebif would you?
I just had a very similar appt. with my PCP. The swollen joints are so painful........some joints are very swollen, like painful lumps everywhere!!
I can't help but think the injections are the cause. I have been on Rebif for almost five years and I really think it is time for a change. In all this time I have only had one really bad relapse, however I have had some progression and now some disability.
My liver enzymes are okay (this time), however my thyroid is acting up and it never has before. I am having bloodwork repeated this week and will making my decision about treatment in the next couple weeks.
Hope you feel better soon and enjoy your company ........Barb

sassy 02-27-2008 12:56 PM

Sorry to hear you still are feeling so puny! I hope something helps you out of this flare!

Take care, rest, and pamper yourself.

lady_express_44 02-27-2008 01:24 PM

This is from wikopedia, which isn't always 100% accurate but I like the simplicity of the information:

"Meloxicam is an NSAID and belongs to the class of drugs called enolic acid group, structurally related to piroxicam. Meloxicam significantly decreased symptoms of pain, function, and stiffness in patients, with a low incidence of gastrointestinal side effects. In models, it exhibits anti-inflammatory, analgesic, and antipyretic activities. Its mechanism of action may be related to prostaglandin synthetase (cyclooxygenase) (COX) inhibition.

Meloxicam has been shown, especially at its low therapeutic dose, to selectively inhibit COX-2 over COX-1.

A primary advantage of the Oxicam family of drugs is their long half-life which permits once-day dosing.

Adverse effects
Meloxicam use can result in gastrointestinal toxicity and bleeding, tinnitus, headache, rash, very dark or black stool (sign of intestinal bleeding). The risk of adverse side effects is lower than with piroxicam, diclofenac, or naproxen. Although meloxicam does inhibit thromboxane A, it does not appear to do so at levels that would interfere with platelet function.

In rare situations, it could cause serious liver disease. If there is a sensation of fatigue and/or liver pain, intake must be ceased."

http://en.wikipedia.org/wiki/Meloxicam

When my spinal lesions are acting up, all I use is Naproxen (which is a similar drug). I personally do feel it helps with the inflammation that occurs with this disease, and it also helps take the "edge" off the pain if used regularly. I take 1500 mg the first day, and then 1000 mg a day (usually for a few weeks), when necessary.

Hope you get to feeling better soon.

Cherie


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