Despite the fact my mom had it and my grandmother (dad's mom) also had this, I don't think it's dominant heredity.

Our chances of getting it increase only slightly. As my brother says, I won the genetic lottery, lol.

I believe there are things that can trigger it, just not sure exactly what.

Like Cherie, I am the only one in my very large family with MS.

I was dx'd in 2001 after an acute exacerbation in December of 2000 followed by another acute exacerbation in March of 2001. I had 2 MRIs, VEP, and an LP that confirmed the dx of MS.

I started on Betaseron in May of that year. Stayed on it until December of '04 when Tysabri was released. Then I switched to Copaxone, which I was intolerant to.

I am now in a clinical trial for Tovaxin. It's a double blind study so I don't know if I am receiving placebo or the real thing. Tomorrow is my last day in the trial.

I am stable right now, the exacerbations have slowed from 4 a year to 2

i come from a large irish family and none of my family or relativees have ms just little old me

They are recognized as a more "uncommon" symptom:

http://www.nationalmssociety.org/abo...che/index.aspx

I often get a relentless "spinal headache" when I go through C-spine lesion attacks.

The headaches I had in the 70's were attributed to sinus headaches at the time, same with the numb mouth and TMJ. Since those symptoms at all came on at the same time as my knee giving out, brainfog, and relentless fatigue . . . it COULD have been a sign of things to come.

Cherie

thank very informative page clicked on a number of the links saved it too,gonna talk to the doc about a few things tomorrow, the headaches have to end, that or just remove my head, i dont use it, i can work around it.