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Hello,
My grandmother was diagnosed with MS in the 70's, based on clinical observation only. However, her disorder is obviously dominant hereditary (50/50 chance of inheritance), and so I'm curious? The latest report that I got from a neurologist in Chicago is that "Most likely, she was misdiagnosed. There's just way too much inheritance at play for this to be an MS case." And so he has diagnosed me with "Autosomal Dominant Spastic Ataxia." I expected him to order additional labwork for me to rule out MS (I already know that I don't have any brain lesions -- but I read that one can have lesions on the spinal cord only and not in the brain at all, in some cases). However, he ordered genetic testing for me instead -- I guess his mind's made up...

Any thoughts?

Thanks,
Christina