Wow Sally, not even close but, thank you for your post...
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There may be no lesions on MRI, with many symptoms and great disability, and then there may be many lesions with no disability.
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I
did not say "are not" silent lesions forming, I said "does not mean there won't be", as anything is possible with MS, i.e., nothing is "concrete"....you are actually talking "apples and oranges"; when I was going by what Ewizabeth stated:
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I'm on Copaxone and not doing so great.
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which "implies" she is having more lesions causing more symptoms (lesions are the scarring that is interrupting the nerve signal due to myelin loss/damage", thus the disability.
http://www.nationalmssociety.org/What%20is%20MS.asp
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But, if Tysabri does lower the risk of exacerbations, that has to be a good thing. It does have a (what did XO say) 10% better efficacy rate at reducing exacerbations, than the CRABS...
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Not sure if you are terribly misinformed or what Sally, but please, let me enlighten you re: Tysabri....there is no if when it comes to it's proven 68% superior efficacy...here is the New England Journal of Medicine's (where some of the most highly respected unbiased medical opinions in the worldopined: "
Results Natalizumab
reduced the risk of sustained progression of disability by 42 percent over two years (hazard ratio, 0.58;
95 percent confidence interval, 0.43 to 0.77; P<0.001)....
Natalizumab reduced the rate of clinical relapse at one year by 68 percent (P<0.001)
and led to an 83 percent reduction in the accumulation of new or enlarging hyperintense lesions, as detected by T2-weighted magnetic resonance imaging (MRI), over two years (mean numbers of lesions, 1.9 with natalizumab and 11.0 with placebo; P<0.001).
There were 92 percent fewer lesions (as detected by gadolinium-enhanced MRI) in the natalizumab group than in the placebo group at both one and two years (P<0.001)." Volume 354:899-910 March 2, 2006 Number 9
Furthermore...
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The Jury's still out on it being better than fried rice, though, since, just like the crabs, the majority of PWMS will not respond favorably to Tysabri
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Wrong again Sally, see the PROVEN DATA recently released: TYSABRI® Demonstrates Improvement in Cognitive Function (
http://www.elan.com/News/full.asp?ID=910099);
TYSABRI® Demonstrate Significant Reduction in Steroid Use and Hospitalizations (
http://www.elan.com/News/full.asp?ID=913012;
TYSABRI® Has Sustained Effect on Relapse Rate for up to Three Years (
http://www.elan.com/News/full.asp?ID=910437);
TYSABRI® Improves Quality of Life (
http://www.elan.com/News/full.asp?ID=840112).
Kinda difficult to argue with proven data, Sally..plus I happen to like "fried rice" alot, and I'd venture a guess that alot of others do too! 
Best wishes to you also.
Lauren
10-23-2006, 04:19 PM
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