Originally Posted by Quixotic1

Second, is that the Criteria only deal with the T2 Hyperintense or enhancing lesions. That is also to say that they only deal with the immune-inflammatory part of our disease. This is the part that is directly responsible for our relapses and remissions (via demyelinationa and repair). But, we know that there is a separate and unclearly related part of direct nerve cell and nerve fiber degeneration/death that is more likely responsible for our accumulation of permanent dsability. There is also the destruction of gray matter via T2 lesions.

Quix